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Constituents of the Underground Parts of Glehnia littoralis

TLDR
The 1,1-diphenyl-2-picrylhydrazyl radical-scavenging assay disclosed quercetin, isoquercet in, rutin, chlorogenic acid, and caffeic acid as the major antioxidative constituents in this crude drug.
Abstract
From the underground parts of Glehnia littoralis FR. Schmidt ex Miquel (Umbelliferae), 26 compounds, including two new lignan glycosides [giehlinosides A (1) and B (2)], a new neolignan glycoside [glehlinoside C (3)], and a new phenylpropanoid glycoside 14-[beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranosyloxyl-3-methoxypropiophenone (4)1, were obtained and their structures were determined by analysis of their spectral data. The 1,1-diphenyl-2-picrylhydrazyl radical-scavenging assay disclosed quercetin (8), isoquercetin (9), rutin (10), chlorogenic acid (11), and caffeic acid (24) as the major antioxidative constituents in this crude drug.

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Glycosides from the root of Iodes cirrhosa.

TL;DR: In the in vitro assays, compound 4 and liriodendrin both showed activity against glutamate-induced PC12 cell damage at 10 (-5) M M, and the validity of J 7,8 and Deltadelta C8-C7 values to distinguish threo and erythro derivatives was discussed.
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Inducible Nitric Oxide Synthase and Cyclooxygenase-2 Participate in Anti-inflammatory Activity of Imperatorin from Glehnia littoralis

TL;DR: Results suggested that imperatorin had anti-inflammatory effects in LPS-stimulated RAW 264.7 cells and Carr-injected mice, respectively, and inhibition of elevated iNOS and COX-2 protein expression as well as neutrophil infiltration of Carr- injected paws may be involved in the beneficial effects of Imperatorin.
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Astonishing diversity of natural surfactants: 5. Biologically active glycosides of aromatic metabolites.

TL;DR: This review article presents 342 aromatic glycosides, isolated from and identified in plants and microorganisms, that demonstrate different biological activities that are of great interest, especially for the medicinal and/or pharmaceutical industries.
Journal ArticleDOI

A practical strategy for the characterization of coumarins in Radix Glehniae by liquid chromatography coupled with triple quadrupole-linear ion trap mass spectrometry

TL;DR: A practical method for the characterization of coumarins in Radix Glehniae by liquid chromatography-mass spectrometry (LC-MS), the first time that these two scan modes have been combined to characterize chemical constituents in traditional Chinese medicine.
Journal ArticleDOI

Constituents from the bark of Tabebuia impetiginosa.

TL;DR: The bark of Tabebuia impetiginosa afforded nineteen glycosides, consisting of four iridoid gly cosides, two lignan glycoside, two isocoumarin glycosided, three phenylethanoid glyCosides and eight phenolic glycosidas, whose structures were determined using both spectroscopic and chemical methods.
References
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Journal ArticleDOI

Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention

TL;DR: It is demonstrated that GSPE is highly bioavailable and provides significantly greater protection against free radicals and free radical-induced lipid peroxidation and DNA damage than vitamins C, E and beta-carotene.
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Carbon-13 NMR studies of flavonoids. III. Naturally occurring flavonoid glycosides and their acylated derivatives

TL;DR: In this article, 13 C NMR spectra for a variety of flavonoid glycosidcs are presented and analyzed, and evidence is presented which demonstrates that 13 C nMR spectroscopy is a valuable technique for distinguishing the sites of methylation, glycosylation and acylation in glycoiides.
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Effects of the Interaction of Tannins with Co-existing Substances. VI. : Effects of Tannins and Related Polyphenols on Superoxide Anion Radical, and on 1, 1-Diphenyl-2-picrylhydrazyl Radical

TL;DR: The scavenging effects of twenty-five tannins including low-molecular polyphenols on the superoxide anion radical (O2-) generated in the hypoxanthine-xanthine oxidase system were estimated by electron spin resonance (ESR) measurements of the adducts formed by 5, 5-dimethyl-1-pyrroline-Noxide (DMPO) and the radical as discussed by the authors.
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Cytotoxic, hepatoprotective and free radical scavenging effects of propolis from Brazil, Peru, the Netherlands and China.

TL;DR: The result of hepatoprotective activity of Brazilian propolis on D-galactosamine (D-GalN)/tumor necrosis factor-alpha (TNF-alpha)-induced cell death in primary cultured mouse hepatocytes were found in accordance with the grade set up by beekeepers in Brazil.
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