Corneal Hysteresis as a Risk Factor for Glaucoma Progression: A Prospective Longitudinal Study
Felipe A. Medeiros,Daniel Meira-Freitas,Daniel Meira-Freitas,Renato Lisboa,Renato Lisboa,Tung-Mei Kuang,Tung-Mei Kuang,Tung-Mei Kuang,Linda M. Zangwill,Robert N. Weinreb +9 more
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TLDR
The prospective longitudinal design of this study supports the role of CH as an important factor to be considered in the assessment of the risk of progression in patients with glaucoma.About:
This article is published in Ophthalmology.The article was published on 2013-08-01 and is currently open access. It has received 232 citations till now. The article focuses on the topics: Glaucoma & Intraocular pressure.read more
Citations
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Journal ArticleDOI
Primary open-angle glaucoma.
Robert N. Weinreb,Christopher Kai-Shun Leung,Jonathan G Crowston,Felipe A. Medeiros,David S. Friedman,Janey L. Wiggs,Keith R Martin +6 more
TL;DR: Primary open-angle glaucoma (POAG) is the most common type and management of POAG includes topical drug therapies and surgery to reduce IOP, although new therapies targeting neuroprotection of RGCs and axonal regeneration are under development.
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The association of blood pressure and primary open-angle glaucoma: a meta-analysis
TL;DR: A role of increased blood pressure in elevated intraocular pressure and possibly in the development of glaucoma is supported, and hypertension was associated with increased intraocular Pressure.
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Primary Open-Angle Glaucoma Preferred Practice Pattern®.
Steven J Gedde,Kateki Vinod,Martha M Wright,Kelly W. Muir,John Lind,Philip P. Chen,Tianjing Li,Steven L. Mansberger +7 more
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Macular and Optic Nerve Head Vessel Density and Progressive Retinal Nerve Fiber Layer Loss in Glaucoma
Sasan Moghimi,Linda M. Zangwill,Rafaella C. Penteado,Kyle Hasenstab,Elham Ghahari,Huiyuan Hou,Mark Christopher,Adeleh Yarmohammadi,Patricia Isabel C. Manalastas,Takuhei Shoji,Christopher Bowd,Robert N. Weinreb +11 more
TL;DR: In this paper, the authors investigated the relationship between macular and peripapillary vessel density and progressive retinal nerve fiber layer (RNFL) loss in patients with mild to moderate primary open-angle glaucoma.
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Aging and ocular tissue stiffness in glaucoma
TL;DR: An improved understanding of the interplay between age-related tissue stiffening and biological responses in the trabecular meshwork and optic nerve head could potentially lead to novel therapeutic strategies for glaucoma treatment.
References
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Random-effects models for longitudinal data
Nan M. Laird,James H. Ware +1 more
TL;DR: In this article, a unified approach to fitting two-stage random-effects models, based on a combination of empirical Bayes and maximum likelihood estimation of model parameters and using the EM algorithm, is discussed.
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The Ocular Hypertension Treatment Study: A Randomized Trial Determines That Topical Ocular Hypotensive Medication Delays or Prevents the Onset of Primary Open-Angle Glaucoma
Michael A. Kass,Dale K. Heuer,Eve J. Higginbotham,Chris A. Johnson,John L. Keltner,J. Philip Miller,Richard K. Parrish,M. Roy Wilson,Mae O. Gordon +8 more
TL;DR: Topical ocular hypotensive medication was effective in delaying or preventing the onset of POAG in individuals with elevated IOP, and clinicians should consider initiating treatment for individuals with ocular hypertension who are at moderate or high risk for developing POAG.
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The advanced glaucoma intervention study (AGIS): 7. the relationship between control of intraocular pressure and visual field deterioration
Fred Ederer,Ma,Douglas E. Gaasterland,E. Kenneth Sullivan,Allen D. Beck,Bruce E. Prum,Marshall N. Cyrlin,Howard S. Weiss +7 more
TL;DR: In both analyses low intraocular pressure is associated with reduced progression of visual field defect, supporting evidence from earlier studies of a protective role for low intracular pressure in visual field deterioration.
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The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma.
Mae O. Gordon,Julia A. Beiser,James D. Brandt,Dale K. Heuer,Eve J. Higginbotham,Chris A. Johnson,John L. Keltner,J. Philip Miller,Richard K. Parrish,M. Roy Wilson,Michael A. Kass +10 more
TL;DR: Baseline age, vertical and horizontal cup-disc ratio, pattern standard deviation, and intraocular pressure were good predictors for the onset of POAG in the OHTS and central corneal thickness was found to be a powerful predictor for the development ofPOAG.
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That BLUP is a Good Thing: The Estimation of Random Effects
TL;DR: In animal breeding, Best Linear Unbiased Prediction (BLUP) as mentioned in this paper is a technique for estimating genetic merits, which can be used to derive the Kalman filter, the method of Kriging used for ore reserve estimation, credibility theory used to work out insurance premiums, and Hoadley's quality measurement plan used to estimate a quality index.