Journal ArticleDOI
Correlation of the internal microviscosity of human erythrocytes to the cell volume and the viscosity of hemoglobin solutions.
Andreas Herrmann,Peter Müller +1 more
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TLDR
The microviscosity of the cytoplasm of human erythrocytes as well as of membrane-free hemoglobin solutions was investigated measuring the rotation of the small spin-label molecule, Tempone, and it was concluded that the intracellular viscosity is not modified by cy toplasmic structures or the cell membrane.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1986-01-23. It has received 35 citations till now. The article focuses on the topics: Microviscosity & Hemoglobin.read more
Citations
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The intrinsic viscosity of biological macromolecules. Progress in measurement, interpretation and application to structure in dilute solution.
Book
Vertebrate red blood cells
TL;DR: Vertebrate red Blood cells :, Vertebrates red Blood Cells :, مرکز فناوری اطلاعات و اشاوρزی
Journal ArticleDOI
Combined Simulation and Experimental Study of Large Deformation of Red Blood Cells in Microfluidic Systems
David J. Quinn,Igor V. Pivkin,Sophie Y. Wong,Keng-Hwee Chiam,Ming Dao,George Em Karniadakis,Subra Suresh +6 more
TL;DR: A cross-sectional area threshold is identified below which the RBC membrane properties begin to dominate its flow behavior at room temperature; at physiological temperatures this effect is less profound.
Journal ArticleDOI
Dielectric spectroscopy of human erythrocytes: investigations under the influence of nystatin
TL;DR: Introduction of an ellipsoidal model with an axis ratio of 1:2 allowed a description that proved to be consistent with dielectrophoresis and electrorotation data and found not to be decreased for cells in Donnan equilibrium, which had leaked out almost completely.
Journal ArticleDOI
Fluorescence measurements of free Ca2+ concentration in human erythrocytes using the Ca2+-indicator fura-2
TL;DR: The use of the fluorescent Ca2+-chelator fura-2 has permitted the use of low concentrations of indicator and cells, thus minimizing the screening effect and the intrinsic fluorescence of haemoglobin, and the influence of viscosity on thefluorescence of this probe is reported.
References
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Journal ArticleDOI
Rotational friction coefficients for spheroids with the slipping boundary condition
Chih‐Ming Hu,Robert Zwanzig +1 more
TL;DR: In this article, the friction coefficients for the uniform rotation of spheroids in a viscous fluid with the slipping boundary condition were computed numerically and reported in tabular form.
Journal ArticleDOI
Spin-Labeled Neurospora Mitochondria
TL;DR: Comparisons of spin-labeled mitochondria results suggest that the hydrocarbon portions of membranes are relatively fluid and are not extensively restricted in motion by association with proteins.
Journal ArticleDOI
Properties of Hemoglobin Solutions in Red Cells
C. M. Gary-Bobo,A. K. Solomon +1 more
TL;DR: A new hypothesis has been developed from thermodynamic principles alone, which predicts that, at constant pH, the net charge on the hemoglobin molecule decreases with increased hemoglobin concentration, and could provide an electrical transducer for osmotic signals.
Journal ArticleDOI
Hard quasispherical model for the viscosity of hemoglobin solutions.
Philip D. Ross,Allen P. Minton +1 more
TL;DR: The viscosity of concentrated hemoglobin solutions of moderate ionic strength at pH values near the isoelectric point may be quantitatively described by the generalized form of a relation commonly applied to suspensions of hard spherical particles.
Related Papers (5)
Intra-erythrocyte microviscosity and diffusion of specifically labelled [glycyl-alpha-13C]glutathione by using 13C n.m.r.
Aging of the erythrocyte. I. Increase in the microviscosity of cell interior as determined by the spin label method.
G. Bartosz,W. Leyko +1 more