Covid-19 fatality is likely overestimated.
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The final case fatality rate (CFR) from SARS-CoV-2, the virus that causes covid-19, will likely be lower than those initially reported.Abstract:
The final case fatality rate (CFR) from SARS-CoV-2, the virus that causes covid-19, will likely be lower than those initially reported.1 Previous reviews of H1N1 and SARS show the systematic inflation of early mortality estimates.23 Early estimates of H1N1’s mortality were susceptible to uncertainty about asymptomatic and subclinical infections, heterogeneity in approaches to diagnostic testing, and biases in confounding, selection, detection, reporting, …read more
Citations
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Machine Learning to Detect Self-Reporting of Symptoms, Testing Access, and Recovery Associated With COVID-19 on Twitter: Retrospective Big Data Infoveillance Study.
Tim K. Mackey,Vidya Purushothaman,Jiawei Li,Neal Shah,Matthew Nali,Cortni Bardier,Bryan A. Liang,Mingxiang Cai,Raphael E. Cuomo +8 more
TL;DR: This study used unsupervised machine learning for the purposes of characterizing self-reporting of symptoms, experiences with testing, and mentions of recovery related to COVID-19.
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Should governments continue lockdown to slow the spread of covid-19?
TL;DR: Until the authors have a meaningful alternative, lockdown is the only thing they can do to prevent further catastrophic spread of the virus, says Edward R Melnick, but John PA Ioannidis argues that any benefits of lockdown depend on its effectiveness and the covid-19 burden.
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SARS-CoV-2 Infection Hospitalization Rate and Infection Fatality Rate Among the Non-Congregate Population in Connecticut.
Shiwani Mahajan,Cesar Caraballo,Shu-Xia Li,Yike Dong,Lian Chen,Sara K. Huston,Rajesh Srinivasan,Carrie A. Redlich,Albert I. Ko,Jeremy S. Faust,Howard P. Forman,Harlan M. Krumholz +11 more
TL;DR: The overall COVID-19 infection hospitalization rate and infection fatality rate were estimated to be 6.86% and 0.95%, respectively, among community residents in Connecticut between March 1 and June 1, 2020, and there was variation in these rate estimates across subgroups.
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Moralization of Covid-19 health response: Asymmetry in tolerance for human costs.
TL;DR: Reducing or eliminating C19 have become moralized, generating asymmetries in evaluations of human suffering, and questioning elimination approaches is morally condemned, a similar response to that found when sacred values are questioned.
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Genomic epidemiology and the role of international and regional travel in the SARS-CoV-2 epidemic in Zimbabwe: a retrospective study of routinely collected surveillance data.
Tapfumanei Mashe,Faustinos Tatenda Takawira,Leonardo de Oliveira Martins,Muchaneta Gudza-Mugabe,Joconiah Chirenda,Manes Munyanyi,Blessmore V Chaibva,Andrew Tarupiwa,Hlanai Gumbo,Agnes Juru,Charles Nyagupe,Vurayai Ruhanya,Isaac K. Phiri,Portia Manangazira,Alexander Goredema,Sydney Danda,Israel Chabata,Janet Jonga,Rutendo Munharira,Kudzai P.E. Masunda,Innocent Mukeredzi,Douglas Mangwanya,Alex Trotter,Thanh Le Viet,Steven Rudder,Gemma L. Kay,David Baker,Gaetan Thilliez,Ana Victoria Gutierrez,Justin O'Grady,Maxwell Hove,Sekesai Mutapuri-Zinyowera,Andrew J. Page,Robert A. Kingsley,Robert A. Kingsley,Gibson Mhlanga +35 more
TL;DR: In this paper, the authors used whole-genome sequencing to describe the molecular epidemiology of the SARS-CoV-2 outbreak and to inform the implementation of effective public health interventions for control in Zimbabwe.
References
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention
Zunyou Wu,Jennifer M. McGoogan +1 more
TL;DR: Hospitalised COVID-19 patients are frequently elderly subjects with co-morbidities receiving polypharmacy, all of which are known risk factors for d
Journal ArticleDOI
How will country-based mitigation measures influence the course of the COVID-19 epidemic?
TL;DR: In this view, COVID-19 has developed into a pandemic, with small chains of transmission in many countries and large chains resulting in extensive spread in a few countries, such as Italy, Iran, South Korea, and Japan and it is unclear whether other countries can implement the stringent measures China eventually adopted.
Journal ArticleDOI
COVID-19 and Italy: what next?
Andrea Remuzzi,Giuseppe Remuzzi +1 more
TL;DR: Analysis of the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Italy might help political leaders and health authorities to allocate enough resources, including personnel, beds, and intensive care facilities, to manage the situation in the next few days and weeks.
Journal ArticleDOI
Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series
Xiao-Wei physician Xu,Xiao-Xin physician Wu,Xian-Gao physician Jiang,Kai-Jin physician Xu,Ling-Jun physician Ying,Chun-Lian physician Ma,Shi-Bo physician Li,Hua-Ying physician Wang,Sheng physician Zhang,Hai-Nv Gao,Jifang Sheng,Hong-Liu physician Cai,Yun-Qing Qiu,Lanjuan Li +13 more
TL;DR: As of early February 2020, compared with patients initially infected with SARS-Cov-2 in Wuhan, the symptoms of patients in Zhejiang province are relatively mild.
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