Journal ArticleDOI
Crinum alkaloids: their chemistry and biology
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TLDR
The current staus of research of free and glycosylated alkaloids occuring in members of the genus Crinum is reviewed in this paper, where the distribution, isolation, spectral properties, structural properties, inter conventions and biological acitivities of these alkaloid are presented.About:
This article is published in Phytochemistry.The article was published on 1985-01-01. It has received 159 citations till now. The article focuses on the topics: Crinum asiaticum & Crinum.read more
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Plant L‐ascorbic acid: chemistry, function, metabolism, bioavailability and effects of processing
Mark W. Davey,M. Van Montagu,Dirk Inzé,Maite Sanmartín,Angelos K. Kanellis,Nicholas Smirnoff,I. J. J. Benzie,John (Sean) J. Strain,D. Favell,J. Fletcher +9 more
TL;DR: The role of L-AA in metabolism and the latest studies regarding its bio- synthesis, tissue compartmentalisation, turnover and catabolism are focused on, as well as the potential to improve the L- AA content of crops.
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Chemistry, biology, and medicinal potential of narciclasine and its congeners.
TL;DR: It is likely that isocarbostyril constituents of the Amaryllidaceae, such as narciclasine, pancratistatin and their congeners, are the most important metabolites responsible for the therapeutic benefits of these plants in the folk medical treatment of cancer.
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Calprotectin (S100A8/S100A9), an inflammatory protein complex from neutrophils with a broad apoptosis-inducing activity.
TL;DR: The findings suggest that calprotectin exerts a regulatory activity in inflammatory processes through its effect on the survival or growth states of cells participating in the inflammatory reaction, and may be a new drug target to control inflammatory reactions.
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Electrochemical approach of anticancer drugs-DNA interaction
Sakandar Rauf,J. Justin Gooding,Kalsoom Akhtar,Muhammad Afzal Ghauri,Moazur Rahman,Munir A. Anwar,Ahmad M. Khalid +6 more
TL;DR: Electrochemical approach can provide new insight into rational drug design and would lead to further understanding of the interaction mechanism between anticancer drugs and DNA.
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Medicinal plants from Riau province, Sumatra, Indonesia. Part 2: Antibacterial and antifungal activity.
TL;DR: The survey of relevant literature indicates that less than 30% of these Angiosperm species have previously been assayed for any form of antimicrobial activity.
References
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Screening of higher plants for biological activities. I. Antimicrobial activity.
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Inhibitors of protein synthesis in eukarytic cells. Comparative effects of some amaryllidaceae alkaloids.
TL;DR: It is concluded that protein synthesis in eukaryotic cells is halted by inhibiting the peptide bone formation step using six compounds obtained from bulbs of the Amaryllidaceae family.
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Alkaloids of Crinum pratense
Shibnath Ghosal,Potharaju H. Rao,Dinesh K. Jaiswal,Yatendra Kumar,August W. Frahm,August W. Frahm +5 more
TL;DR: Pratorinine is a new phenanthridone alkaloid and anhydrolycorin-7-one was known before only as a synthetic compound and the physiological significance of hippadine is appraised.
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Approaches to the synthesis of masked p-quinone methides. applications to the total synthesis of (.+-.)-cherylline
TL;DR: In this paper, the synthesis and chemistry of p-quinone methide ketals, prepared from monoketals 9a-c and a-tri-methylsilylamides or phosphoranes, is discussed within the context of the total synthesis of Amaryllidaceae alkaloid cherylline.
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Narciclasine: an antitumour alkaloid which blocks peptide bond formation by eukaryotic ribosomes.
TL;DR: The results presented in this communication show that narciclasine inhibits protein synthesis in rabbit reticulocyte and yeast cell-free systems by blocking peptide bond formation at the ribosome level.