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Journal ArticleDOI

Current research status of fish immunostimulants

Masahiro Sakai
- 01 Mar 1999 - 
- Vol. 172, Iss: 1, pp 63-92
TLDR
In conclusion, immunostimulants can reduce the losses caused by disease in aquaculture; however, they may not be effective against all diseases.
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This article is published in Aquaculture.The article was published on 1999-03-01. It has received 1239 citations till now. The article focuses on the topics: Immunostimulant.

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Citations
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Journal ArticleDOI

Probiotic Bacteria as Biological Control Agents in Aquaculture

TL;DR: This review describes the state of the art of probiotic research in the culture of fish, crustaceans, mollusks, and live food, with an evaluation of the results obtained so far.
Journal ArticleDOI

Innate immunity of fish (overview).

TL;DR: The innate immune system is the only defence weapon of invertebrates and a fundamental defence mechanism of fish and plays an instructive role in the acquired immune response and homeostasis and is therefore equally important in higher vertebrates.
Journal ArticleDOI

The role of probiotics in aquaculture

TL;DR: This review provides a summary of the use of probiotics for prevention of bacterial diseases in aquaculture, with a critical evaluation of results obtained to date.
Journal ArticleDOI

The current status and future focus of probiotic and prebiotic applications for salmonids

TL;DR: The application of probiotics and prebiotics may result in elevated health status, improved disease resistance, growth performance, body composition, reduced malformations and improved gut morphology and microbial balance.
Journal ArticleDOI

Probiotics in aquaculture

TL;DR: There is accumulating evidence that probiotics are effective at inhibiting a wide range of fish pathogens, but the reasons for the inhibitions are often unstated.
References
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Journal ArticleDOI

Role of nitric oxide synthesis in macrophage antimicrobial activity.

TL;DR: It is suggested that synthesis of NO mediates much of the antimicrobial activity of mouse macrophages against some fungal, helminthic, protozoal and bacterial pathogens.
Journal ArticleDOI

Dietary intake of immunostimulants by rainbow trout affects non-specific immunity and protection against furunculosis

TL;DR: A challenge with the virulent pathogen that causes furunculosis, Aeromonas salmonicida, showed that the immunostimulated groups of fish were more resistant to the disease, confirming the potential use of these substances in fish culture for the prevention of disease.
Journal ArticleDOI

Immunostimulants, adjuvants, and vaccine carriers in fish: Applications to aquaculture

TL;DR: Concepts of use of immunostimulants, adjuvants, and vaccine carriers in fish hold tremendous potential for use in fish farms, hatcheries, and aquaculture facilities to reduce losses from infectious diseases.
Journal ArticleDOI

Bactericidal activity of human lactoferrin: sensitivity of a variety of microorganisms.

TL;DR: Variable susceptibilities for a variety of different microorganisms are demonstrated and it appears that there may be a relation between virulence and resistance to lactoferrin.
Journal ArticleDOI

Immunostimulation of tiger shrimp (Penaeus monodon) hemocytes for generation of microbicidal substances: analysis of reactive oxygen species.

TL;DR: NBT staining was used to determine the presence of superoxide anions produced by tiger shrimp hemocytes attached to a coverslip, and it was found that beta-glucan had the strongest stimulative effect, followed by zymosan and PMA (7.2 and 2.6 nmol/mg, respectively).
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