Journal ArticleDOI
Cytokinetics of argentaffin cells in mouse intestinal mucosa.
Reads0
Chats0
TLDR
Diazo-positive cells in mouse duodenal mucosa proliferate only in the same zone as epithelial cells (bottom and lower parts of the crypts) and it is suggested that a special cytokinetic behaviour appears earlier than morphological argentaffin differentiation.Abstract:
Diazo-positive cells in mouse duodenal mucosa proliferate only in the same zone as epithelial cells (bottom and lower parts of the crypts). Their rate of proliferation as well as their speed of migration into the villi are slower than those of epithelial cells, but to a minor extent only. It is suggested that a special cytokinetic behaviour appears earlier than morphological argentaffin differentiation.read more
Citations
More filters
Journal ArticleDOI
Proliferation of enterochromaffinlike cells in omeprazole-treated hypergastrinemic rats.
Y. Tielemans,Y. Tielemans,Rolf Håkanson,Rolf Håkanson,Frank Sundler,Frank Sundler,G. Willems,G. Willems +7 more
TL;DR: The data indicate that the omeprazole-evoked ECL cell hyperplasia is a result of accelerated self-replasia, and the positive correlation between the plasma gastrin concentration and the ECL Cell labeling index is compatible with a causal relationship between circulating gastrin levels and increased ECLcell density.
Journal ArticleDOI
Serum gastrin concentration affects the self replication rate of the enterochromaffin like cells in the rat stomach.
TL;DR: The observed correlation between the enterochromaffin like cell labelling indices and the serum gastrin concentration supports the hypothesis that entero Chromaffinlike cell proliferation is influenced by serum Gastrin.
Journal ArticleDOI
Population Kinetics of Antral Gastrin Cells in the Mouse
Thérèse Lehy,G. Willems +1 more
TL;DR: Analysis of the labeling index curves obtained during and after the administration of [3H]thymidine confirmed that the majority of the Gastrin cells were renewed through replication of other gastrin cells, however, differentiation of a fraction of this gastrin cell population from "other" cells in the antrum could not be excluded.
Journal ArticleDOI
Tritiated thymidine autoradiographic study on origin and renewal of gastrin cells in antral area of hamsters
Sotaro Fujimoto,Takanori Hattori,Kunihiko Kimoto,Shigeo Yamashita,Setsuya Fujita,Keiichi Kawai +5 more
TL;DR: It is found that most gastrin cells differentiate functionally within 5 days, and the turnover time of the Gastrin cells (a half-life of the cells) was estimated to be 10–15 days.
Journal ArticleDOI
Cellular kinetics of gastrointestinal mucosa, with special reference to gut endocrine cells.
TL;DR: Investigation of the kinetics of the antral G cells in the hamster, G cells and S cell in the rat duodenum by the combined utilization of 3H-thymidine autoradiography with immunohistochemistry confirmed that these cells are derived from the same precursor cells as the other mucosal cells of the gastrointestinal tract.
References
More filters
Book
Histochemistry, theoretical and applied
TL;DR: The new Pearse bids fair to become the leader, even amongst so notable a collection of books devoted entirely or largely to histochemical techniques.
Journal ArticleDOI
Cell population kinetics in the intestinal epithelium of the mouse
Journal ArticleDOI
Cell proliferation studies in the intestinal epithelium of the rat. I. Determination of the kinetic parameters
TL;DR: Cells at the top of the proliferation zone show considerable uniformity in the length of the periods of the cycle, and cells in mitosis and cells which incorporate 3H-thymidine are presented for the upper jejunum of male August rats.
Journal ArticleDOI
The duodenal progenitor population. III. The progenitor cell cycle of principal, goblet and paneth cells
TL;DR: It appears from the data that the three cell types of the adult duodenal crypt comprise independent populations capable of self-renewal, and the existence of causal relationships between the positioning of the proliferative cells types in the duodensal microenvironment and their respective cycle durations is suggested.
Journal ArticleDOI
An autoradiographic study of the renewal of argentaffin cells in human rectal mucosa.
TL;DR: The generation time of individual cells appeared to vary greatly, some remaining for long periods in the G2 or G1 (postmitotic) portions of interphase.
Related Papers (5)
Argentaffin and other "endocrine" cells of the small intestine in the adult mouse. II. Renewal.
M. N. Ferreira,C. P. Leblond +1 more