Journal ArticleDOI
Definition of the metabolic syndrome: current proposals and controversies.
Efrain Reisin,Martin A. Alpert +1 more
TLDR
A unified definition that recognizes the increased biologic activity of the upper visceral fatty tissue and the strong association of abdominal obesity as a leading part of metabolic syndrome is proposed herein.About:
This article is published in The American Journal of the Medical Sciences.The article was published on 2005-12-01. It has received 64 citations till now. The article focuses on the topics: Abdominal obesity & Metabolic syndrome.read more
Citations
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Journal Article
Non alcoholic fatty liver disease and metabolic syndrome.
TL;DR: Current knowledge on the epidemiology, pathophysiology and diagnosis of both NAFLD and metabolic syndrome and the findings that strongly support the association of nonalcoholic fatty liver disease as a possible component in the cluster of metabolic syndrome are summarized.
Journal ArticleDOI
Prevalence of the metabolic syndrome is increased in rheumatoid arthritis and is associated with coronary atherosclerosis.
Cecilia P. Chung,Annette Oeser,Joseph F. Solus,Ingrid Avalos,Tebeb Gebretsadik,Ayumi Shintani,Paolo Raggi,Tuulikki Sokka,Theodore Pincus,C. Michael Stein +9 more
TL;DR: Patients with rheumatoid arthritis have a higher prevalence of the metabolic syndrome than control subjects and inflammation-associated metabolic syndrome is a mechanism that may contribute to increased coronary-artery atherosclerosis in RA.
Journal ArticleDOI
Role of magnesium in hypertension
Bruno Sontia,Rhian M. Touyz +1 more
TL;DR: The role of magnesium in the regulation of vascular function and blood pressure is addressed, the implications of magnesium deficiency in experimental and clinical hypertension, in metabolic syndrome and in pre-eclampsia are discussed and the therapeutic value is unclear.
Journal ArticleDOI
Improvement in insulin resistance and reduction in plasma inflammatory adipokines after weight loss in obese dogs
Alexander J. German,M. Hervera,Leif Hunter,Shelley L. Holden,Penelope J. Morris,Vincent Biourge,Paul Trayhurn +6 more
TL;DR: It is demonstrated that in obese dogs, insulin resistance correlates with degree of adiposity, and weight loss improves insulin sensitivity, suggesting improvement of a subclinical inflammatory state associated with obesity.
Journal ArticleDOI
The evolving definitions and increasing prevalence of the metabolic syndrome.
Sophie Desroches,Benoît Lamarche +1 more
TL;DR: The present review aims to discuss the different definitions of the metabolic syndrome, focusing on their application in clinical or research settings, and a brief overview of the increasing prevalence of the MetS.
References
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Journal ArticleDOI
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation.
K. G. M. M. Alberti,Paul Zimmet +1 more
TL;DR: A WHO Consultation has taken place in parallel with a report by an American Diabetes Association Expert Committee to re‐examine diagnostic criteria and classification of diabetes mellitus and is hoped that the new classification will allow better classification of individuals and lead to fewer therapeutic misjudgements.
Journal Article
Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Scott M. Grundy,Diane M. Becker,Luther T. Clark,Richard S. Cooper,Margo A. Denke,James P. Howard,Donald B. Hunninghake,D. Roger Illingworth,Russell V. Luepker,Patrick E. McBride,James M. McKenney,Richard C. Pasternak,Neil J. Stone,Linda Van Horn +13 more
Journal ArticleDOI
Role of Insulin Resistance in Human Disease
TL;DR: The possibility is raised that resistance to insulin-stimulated glucose uptake and hyperinsulinemia are involved in the etiology and clinical course of three major related diseases— NIDDM, hypertension, and CAD.
Journal ArticleDOI
Definition of Metabolic Syndrome Report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition
TL;DR: Although ATP III identified CVD as the primary clinical outcome of the metabolic syndrome, most people with this syndrome have insulin resistance, which confers increased risk for type 2 diabetes, when diabetes becomes clinically apparent, CVD risk rises sharply.
Journal ArticleDOI
The metabolic syndrome
TL;DR: The pathophysiology seems to be largely attributable to insulin resistance with excessive flux of fatty acids implicated, and a proinflammatory state probably contributes to the metabolic syndrome.
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Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation.
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Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Scott M. Grundy,David W. Bilheimer,Alan Chait,Luther T. Clark,Margo A. Denke,Richard J. Havel,William R. Hazzard,Stephen B. Hulley,Donald B. Hunninghake,Robert A. Kreisberg,Penny M. Kris-Etherton,James M. McKenney,Michael A. Newman,Ernst J. Schaefer,Burton E. Sobel,Carolyn Somelofski,Milton C. Weinstein,H. Bryan Brewer,James I. Cleeman,Karen A. Donato,Nancy D. Ernst,Jeffrey M. Hoeg,Basil M. Rifkind,Jacques E. Rossouw,Christopher T. Sempos,Joanne M. Gallivan,Maureen N. Harris,Laurie Quint-Adler +27 more