Journal ArticleDOI
Desogestrel only contraceptive pill versus sequential contraceptive vaginal ring in the treatment of rectovaginal endometriosis infiltrating the rectum: a prospective open-label comparative study
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This article is published in Fertility and Sterility.The article was published on 2013-09-01. It has received 24 citations till now. The article focuses on the topics: Vaginal ring & Desogestrel.read more
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Journal ArticleDOI
Novel drug delivery methods for improving efficacy of endometriosis treatments.
Simone Garzon,Antonio Simone Laganà,Fabio Barra,Jvan Casarin,Antonella Cromi,Ricciarda Raffaelli,Stefano Uccella,Massimo Franchi,Fabio Ghezzi,Simone Ferrero +9 more
TL;DR: This review aims to provide the reader with a complete overview of available evidence about alternative and novel drug delivery methods for endometriosis pharmacotherapy and highlight new research lines.
Journal ArticleDOI
"Per vaginam" topical use of hormonal drugs in women with symptomatic deep endometriosis: a narrative literature review.
Laura Buggio,Caterina Lazzari,Ermelinda Monti,Giussy Barbara,Nicola Berlanda,Paolo Vercellini +5 more
TL;DR: The vaginal route represents a scarcely explored modality for drug administration and high local hormonal concentrations might achieve a greater effect on endometriotic lesions compared with alternative routes.
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The Combined Contraceptive Vaginal Ring: an Update
Marie-Soleil Wagner,Amanda Black +1 more
TL;DR: The combined contraceptive vaginal ring is as effective as combined oral contraceptive pills with similar side effects but better cycle control and may have many non-contraceptive benefits including a positive effect on sexual function, dysmenorrhea, premenstrual syndrome, and heavy menstrual bleeding.
La place de la sage-femme libérale dans la stratégie diagnostique de l’endométriose
TL;DR: In this article, the authors analyse the connaissances des sages-femmes liberales concernant l’endometriose and leurs pratiques lorsque celle-ci est suspectee.
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Consensus canadien sur la contraception (3e partie de 4) : chapitre 8 – contraception à progestatif seul
Amanda Black,Edith Guilbert,Dustin Costescu,Sheila Dunn,William A. Fisher,Sari Kives,Melissa Mirosh,Wendy V. Norman,Helen Pymar,Robert L. Reid,Geneviève Roy,Hannah Varto,Ashley Waddington,Marie-Soleil Wagner,Anne Marie Whelan +14 more
TL;DR: La qualité des résultats a été évaluée au moyen des critères décrits dans le rapport du Groupe d'étude canadien sur les soins de santé préventifs.
References
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Journal ArticleDOI
Reevaluating response and failure of medical treatment of endometriosis: a systematic review.
TL;DR: Few studies of medical therapies for endometriosis report outcomes that are relevant to patients, and many women gain only limited or intermittent benefit from treatment.
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Bladder Endometriosis: A Systematic Review of Pathogenesis, Diagnosis, Treatment, Impact on Fertility, and Risk of Malignant Transformation
Umberto Leone Roberti Maggiore,Simone Ferrero,Massimo Candiani,Edgardo Somigliana,Paola Viganò,Paolo Vercellini +5 more
TL;DR: Current evidence does not support the removal of bladder endometriotic lesions because of the potential risk of malignant transformation since this phenomenon is exceedingly rare, and the review provides a useful tool to guide physicians in the management of this complex condition.
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Treatment of pain associated with deep endometriosis: alternatives and evidence
TL;DR: Surgical excision of DIE should be considered in patients with pain symptoms persisting after first-line hormonal therapies, and the benefits of surgery in terms of pain improvement should be always balanced with the risk of intraoperative complications.
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Medical treatment of endometriosis-related pain
Paolo Vercellini,Laura Buggio,Maria Pina Frattaruolo,Alessandra Borghi,Dhouha Dridi,Edgardo Somigliana +5 more
TL;DR: A stepwise approach is suggested, starting with OCs or low-cost progestogens, and stepping up to high-cost drugs only in case of inefficacy or intolerance, as the individual response to different drugs is variable.
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Comparative, open-label prospective study on the quality of life and sexual function of women affected by endometriosis-associated pelvic pain on 2 mg dienogest/30 µg ethinyl estradiol continuous or 21/7 regimen oral contraceptive.
TL;DR: Women on DNG/EE COC continuous regimen reported a reduction of endometriosis-associated pelvic pain and there was an improvement of their sexual activity and their QoL that was better than the D NG/EE 21/7 conventional regimen.