Development and first validation of the COPD Assessment Test
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TLDR
The aim of the present study was to develop a short validated patient-completed questionnaire, the COPD Assessment Test (CAT), assessing the impact of COPD on health status, which has good measurement properties, is sensitive to differences in state and should provide a valid, reliable and standardised measure of COPd health status with worldwide relevance.Abstract:
There is need for a validated short, simple instrument to quantify chronic obstructive pulmonary disease (COPD) impact in routine practice to aid health status assessment and communication between patient and physician. Current health-related quality of life questionnaires provide valid assessment of COPD, but are complex, which limits routine use. The aim of the present study was to develop a short validated patient-completed questionnaire, the COPD Assessment Test (CAT), assessing the impact of COPD on health status. 21 candidate items identified through qualitative research with COPD patients were used in three prospective international studies (Europe and the USA, n51,503). Psychometric and Rasch analyses identified eight items fitting a unidimensional model to form the CAT. Items were tested for differential functioning between countries. Internal consistency was excellent: Cronbach's a50.88. Test re-test in stable patients (n553) was very good (intra-class correlation coefficient 0.8). In the sample from the USA, the correlation with the COPD-specific version of the St George's Respiratory Questionnaire was r50.80. The difference between stable (n5229) and exacerbation patients (n567) was five units of the 40-point scale (12%; p,0.0001). The CAT is a short, simple questionnaire for assessing and monitoring COPD. It has good measurement properties, is sensitive to differences in state and should provide a valid, reliable and standardised measure of COPD health status with worldwide relevance.read more
Citations
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COPD assessment test and FEV 1 : do they predict oxygen uptake in COPD?
Luiz Carlos S Carvalho-Jr,Renata Trimer,Guilherme Pt Arêas,Guilherme Pt Arêas,Flávia Cr Caruso,Katiany Tl Zangrando,Soraia Pilon Jürgensen,José Carlos Bonjorno,Claudio Ricardo de Oliveira,Ramona Cabiddu,Renata Gonçalves Mendes,Audrey Borghi-Silva +11 more
TL;DR: COPD patients’ maximum aerobic capacity has a significant correlation with easily accessible and widely used clinical variables, such as the CATs and FEV1, which can be used to estimate peak VO2.
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Chronic obstructive pulmonary disease: clinical review and update on consensus guidelines.
TL;DR: An evidence-based clinical review on COPD is provided, with a focus on internists as the target audience, and the global impact of COPD remains strikingly large.
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Risk factors for depression in patients with chronic obstructive pulmonary disease
TL;DR: Low BMI, low FEV1, and high CAT score were identified as independent risk factors for depression in patients with COPD.
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Screening heroin smokers attending community drug clinics for change in lung function: A cohort study
Rebecca Nightingale,Kevin Mortimer,Emanuele Giorgi,Paul Walker,Marie Stolbrink,Tara Byrne,Kerry Marwood,Sally Morrison-Griffiths,Susan Renwick,Jamie Rylance,Jamie Rylance,Hassan Burhan +11 more
TL;DR: In this paper, a cohort of heroin smokers with COPD was followed for 18 to 24 months, and respiratory symptoms were measured by the Medical Research Council Dyspnea Scale (MRC) and the COPD Assessment Tool (CAT), and postbronchodilator spirometry was performed.
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Sertraline hydrochloride treatment for patients with stable chronic obstructive pulmonary disease complicated with depression: a randomized controlled trial.
Yuan-qiang He,Yulong Zheng,Chuan-Qin Xu,Haichen Yang,Ziyu Wang,Liyang Zhou,Yufeng Wan,Donghui Zheng,Jing Zhu +8 more
TL;DR: There is a lack of randomized controlled trials to assess the effects of pharmacological treatments in patients with stable chronic obstructive pulmonary disease (COPD) complicated with moderate or severe depression.
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