Journal ArticleDOI
Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: A multicenter prospective study (the FIBROSTIC study)
Françoise Degos,Paul Perez,Bruno Roche,Amel Mahmoudi,Julien Asselineau,Hélène Voitot,Pierre Bedossa +6 more
TLDR
The diagnostic accuracy of non-invasive tests was high for cirrhosis, but poor for significant fibrosis, and liver biopsy is warranted to diagnose intermediate stages of fibrosis.About:
This article is published in Journal of Hepatology.The article was published on 2010-12-01. It has received 421 citations till now. The article focuses on the topics: Hepatitis & METAVIR Fibrosis Score.read more
Citations
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EASL Recommendations on Treatment of Hepatitis C
Jean-Michel Pawlotsky,Alessio Aghemo,Geoffrey Dusheiko,Xavier Forns,Massimo Puoti,Christophe Sarrazin +5 more
TL;DR: The optimal management of patients with acute and chronic HCV infections in 2018 and onwards is described, as well as developments in diagnostic procedures and improvements in therapy and prevention.
Journal ArticleDOI
EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis.
TL;DR: Liver biopsy gives a snapshot and not an insight into the dynamic changes during the process of fibrogenesis, so immunohistochemical evaluation of cellular markers such as smooth muscle actin expression for hepatic stellate cell activation, cytokeratin 7 for labeling ductular proliferation or CD34 for visualization of sinusoidal endothelial capillarization can provide additional ‘‘functional’’ information.
EASL Clinical Practice Guidelines: Management of hepatitis C virus infection European Association for the Study of the Liver ⇑
TL;DR: The EASL CPGs on the management of HCV infection will be updated on a regular basis upon approval of additional novel therapies, and will apply to therapies that are approved at the time of their publication.
Journal ArticleDOI
Hepatitis B virus infection
TL;DR: Developing new therapies that can improve HBsAg clearance and virological cure is warranted because long-term antiviral treatment can reverse cirrhosis and reduce hepatocellular carcinoma.
Journal ArticleDOI
WFUMB Guidelines and Recommendations for Clinical Use of Ultrasound Elastography: Part 2: Breast
Richard G. Barr,Kazutaka Nakashima,Dominique Amy,David O. Cosgrove,André Farrokh,F. K. W. Schäfer,Jeffrey C. Bamber,Laurent Castera,Byung Ihn Choi,Yi-Hong Chou,Christoph F. Dietrich,Hong Ding,Giovanna Ferraioli,Carlo Filice,Mireen Friedrich-Rust,Timothy J. Hall,Kathryn R. Nightingale,Mark L. Palmeri,Tsuyoshi Shiina,Shinichi Suzuki,Ioan Sporea,Stephanie R. Wilson,Masatoshi Kudo +22 more
TL;DR: The World Federation for Ultrasound in Medicine and Biology has produced these guidelines for the use of elastography techniques in liver disease, aimed at assessing the usefulness ofElastography in the management of liver diseases.
References
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Journal ArticleDOI
Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach.
TL;DR: A nonparametric approach to the analysis of areas under correlated ROC curves is presented, by using the theory on generalized U-statistics to generate an estimated covariance matrix.
Journal ArticleDOI
A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C
Chun-Tao Wai,Joel K. Greenson,Robert J. Fontana,John D. Kalbfleisch,Jorge A. Marrero,Hari S. Conjeevaram,Anna S.F. Lok +6 more
TL;DR: It is shown that a simple index using readily available laboratory results can identify CHC patients with significant fibrosis and cirrhosis with a high degree of accuracy and may decrease the need for staging liver biopsy specimens among patients with CHC.
Journal ArticleDOI
An algorithm for the grading of activity in chronic hepatitis C
Pierre Bedossa,Thierry Poynard +1 more
TL;DR: A simple algorithm that generates a single activity score based on basic pathological features in chronic hepatitis C is proposed and tested, showing its accuracy is as high as that obtained using a statistical approach.
Journal ArticleDOI
The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews
TL;DR: In this article, an evidence-based quality assessment tool called QUADAS was proposed to assess the quality of primary studies of diagnostic accuracy, based on the results of three previously conducted reviews of the diagnostic literature.
Book
Users' Guides to the Medical Literature
Gordon H. Guyatt,Drummond Rennie +1 more
TL;DR: Without a way of critically appraising the information they receive, clinicians are relatively helpless in deciding what new information to learn and decide how to modify their practice.