Dosage form modification and oral drug delivery in older people.
TLDR
In this paper, the authors reviewed the challenges associated with administering medicines to older people, and issues with dosage form modification, and proposed novel dosage forms in development are promising and may help overcome some of the issues.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2018-10-01 and is currently open access. It has received 46 citations till now.read more
Citations
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Recent advances of oral film as platform for drug delivery.
TL;DR: In this paper, a review of newly developed oral drug delivery films is presented, discussing their formulation strategies, manufacturing methods as well as advantages and limitations, and future perspectives are also provided.
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Pill swallowing in Parkinson's disease: A prospective study based on flexible endoscopic evaluation of swallowing.
Carsten Buhmann,Moritz Bihler,Katharina Emich,Ute Hidding,Monika Pötter-Nerger,Christian Gerloff,Almut Niessen,Till Flügel,Jana-Christina Koseki,Julie Cläre Nienstedt,Christina Pflug +10 more
TL;DR: Dysphagia of medication occurs preferentially in advanced disease stages, and an assessment of pill swallowing using FEES is suggested at least in patients reporting swallowing problems.
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Challenges and innovations of delivering medicines to older adults
TL;DR: Current challenges and novel approaches to delivering medications to older adults are summarized and discussed.
Journal ArticleDOI
Tablet Scoring: Current Practice, Fundamentals, and Knowledge Gaps
TL;DR: Evaluating the advantages and inconveniences associated with tablet scoring/portioning and identifying factors in the formulation and the manufacturing of tablets that influence tablet partitioning.
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Appropriateness of oral dosage form modification for aged care residents: a video-recorded observational study
Aida Sefidani Forough,Esther Lau,Esther Lau,Kathryn J. Steadman,Kathryn J. Steadman,Greg Kyle,Julie A. Y. Cichero,Julie A. Y. Cichero,Jose Manuel Serrano Santos,Lisa Nissen,Lisa Nissen +10 more
TL;DR: Healthcare workers in aged care facilities need to be supported and upskilled with effective training to promote the best and safest practices of ODF modification.
References
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Clinical consequences of polypharmacy in elderly
TL;DR: It is shown that well-designed interprofessional intervention studies that focus on enrolling high-risk older patients with polypharmacy have shown that they can be effective in reducing aspects of unnecessary prescribing with mixed results on distal health outcomes.
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Aspiration pneumonia and dysphagia in the elderly.
Paul E. Marik,Danielle Kaplan +1 more
TL;DR: Elderly patients with clinical signs suggestive of dysphagia and/or who have CAP should be referred for a swallow evaluation and consideration for treatment with an angiotensin-converting enzyme inhibitor.
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Literacy and Misunderstanding Prescription Drug Labels
Terry C. Davis,Michael S. Wolf,Pat F. Bass,Jason A. Thompson,Hugh H. Tilson,Marolee Neuberger,Ruth M. Parker +6 more
TL;DR: Lower literacy and a greater number of medications being taken were associated with patient misunderstanding of pill bottle labels, and low literacy would be associated with higher rates of misunderstanding and incorrect demonstration.
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Development of international terminology and definitions for texture-modified foods and thickened fluids used in dysphagia management: the IDDSI framework
Julie A. Y. Cichero,Peter Lam,Catriona M. Steele,Catriona M. Steele,Ben Hanson,Jianshe Chen,Roberto Oliveira Dantas,Janice Duivestein,Jun Kayashita,Caroline Lecko,Joseph Murray,Mershen Pillay,Mershen Pillay,Luis F. Riquelme,Luis F. Riquelme,Soenke Stanschus +15 more
TL;DR: The IDDSI Framework involves a continuum of 8 levels identified by numbers, text labels, color codes, definitions, and measurement methods and is recommended for implementation throughout the world.
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Low Literacy Impairs Comprehension of Prescription Drug Warning Labels
Terry C. Davis,Michael S. Wolf,Pat F. Bass,Mark Middlebrooks,Estela M. Kennen,David W. Baker,Charles L. Bennett,Ramon Durazo-Arvizu,Anna Bocchini,Stephanie Savory,Ruth M. Parker +10 more
TL;DR: Warning labels should be developed with consumer participation, especially with lower literate populations, to ensure comprehension of short, concise messages created with familiar words and recognizable icons.