Patent
Droplet manipulation device
TLDR
In this paper, the authors provided methods for manipulating droplets by placing the droplet on a surface comprising an array of electrodes and a substantially co-planer array of reference elements.Abstract:
Methods are provided for manipulating droplets. The methods include providing the droplet on a surface comprising an array of electrodes and a substantially co-planer array of reference elements, wherein the droplet is disposed on a first one of the electrodes, and the droplet at least partially overlaps a second one of the electrodes and an intervening one of the reference elements disposed between the first and second electrodes. The methods further include activating the first and second electrodes to spread at least a portion of the droplet across the second electrode and deactivating the first electrode to move the droplet from the first electrode to the second electrode.read more
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Patent
Gene sequencing chip and gene sequencing method
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Patent
Digital microfluidic devices including dual substrates with thin-film transistors and capacitive sensing
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Patent
Detecting compounds in microfluidic droplets using mass spectrometry
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Patent
Digital microfluidic devices
TL;DR: In this article, the authors discuss the routing of droplet control signals in a digital microfluidic device, which can comprise a first substrate having droplet controllers in one layer and at least some control signal lines in another layer, and these two layers are separated by a layer of dielectric material patterned with VIAs.
Patent
Fogdrop concentration detection device and method
TL;DR: In this paper, a fogdrop concentration detection device consisting of fogdrop collector, fogdrop balance detection circuit, signal conditioning circuit and voltage sensor is presented. And the control module is connected with the fog drop collector, the voltage sensor, the first flow sensor and the second flow sensor respectively.
References
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Journal ArticleDOI
Monolithic microfabricated valves and pumps by multilayer soft lithography
TL;DR: An extension to the soft lithography paradigm, multilayersoft lithography, with which devices consisting of multiple layers may be fabricated from soft materials is described, to build active microfluidic systems containing on-off valves, switching valves, and pumps entirely out of elastomer.
Journal ArticleDOI
High-performance heat sinking for VLSI
TL;DR: In this paper, a water-cooled integral heat sink for silicon integrated circuits has been designed and tested at a power density of 790 W/cm2, with a maximum substrate temperature rise of 71°C above the input water temperature.
Journal ArticleDOI
Microfluidics: Fluid physics at the nanoliter scale
Todd M. Squires,Stephen R. Quake +1 more
TL;DR: A review of the physics of small volumes (nanoliters) of fluids is presented, as parametrized by a series of dimensionless numbers expressing the relative importance of various physical phenomena as mentioned in this paper.
Journal ArticleDOI
Fabrication of microfluidic systems in poly(dimethylsiloxane)
J.C. McDonald,David C. Duffy,Janelle R. Anderson,Daniel T. Chiu,Hongkai Wu,Olivier Schueller,George M. Whitesides +6 more
TL;DR: Fabrication of microfluidic devices in poly(dimethylsiloxane) (PDMS) by soft lithography provides faster, less expensive routes to devices that handle aqueous solutions.
Journal ArticleDOI
Miniaturized total chemical analysis systems: A novel concept for chemical sensing
TL;DR: In this paper, a modular construction of a miniaturized "total chemical analysis system" is proposed, and theoretical performances of such systems based on flow injection analysis, chromatography and electrophoresis are compared with those of existing chemical sensors and analysis systems.