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Journal ArticleDOI

Dual pathways connecting the dorsolateral prefrontal cortex with the hippocampal formation and parahippocampal cortex in the rhesus monkey

Patricia S. Goldman-Rakic, +2 more
- 01 Jul 1984 - 
- Vol. 12, Iss: 3, pp 719-743
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TLDR
It is speculated that each of these prefrontal projections may carry highly specific information into the hippocampus, whereas the reciprocal projections may allow retrieval by prefrontal cortex of memories stored in the hippocampus.
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This article is published in Neuroscience.The article was published on 1984-07-01. It has received 730 citations till now. The article focuses on the topics: Subiculum & Prefrontal cortex.

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Single-photon emission computed tomography with 99mTc-exametazime in unmediated schizophrenic patients

TL;DR: SPECT provides a readily available method to examine the relationship between symptom pattern and regional brain metabolism in psychotic patients and associations between certain schizophrenic syndrome scores and tracer uptake to a number of cortical and subcortical brain regions.
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Frontal units of the monkey coding the associative significance of visual and auditory stimuli.

TL;DR: The results indicate that some frontal units participate in the crossmodal coding of the associative significance of the stimulus independent of its physical properties, and most frontal units play different roles depending on the modality of the stimuli.
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Disruption of the dorsolateral prefrontal cortex facilitates the consolidation of procedural skills

TL;DR: The hypothesis that functions in the dorsolateral prefrontal cortex (DLPFC) that support declarative memory formation indirectly reduce the formation of procedural representations are tested and support the hypothesis of interference between Declarative and procedural consolidation processes.
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Differential fractional anisotropy abnormalities in adolescents with ADHD or schizophrenia.

TL;DR: Diffusion tensor imaging was used to compare white matter integrity, as indicated by fractional anisotropy (FA), in adolescents with schizophrenia or ADHD and healthy controls, and the two disorders generally demonstrated distinct patterns of abnormal connectivity suggesting that common cognitive and behavioral deficits derive from distinct sources.
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Lesions Affecting the Parahippocampal Cortex Yield Spatial Memory Deficits in Humans

TL;DR: The results show that the PHC is a critical component for spatial memory in humans and suggest that (i) extrahippocampal spatial memory functions of the medial temporal lobe may be largely confined to thePHC, and (ii) damage to connections between cortices involved in spatial cognition and rostral regions of the temporal lobe is unlikely to account for the observed spatial memory deficits with PHC lesions.
References
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Book

The Hippocampus as a Cognitive Map

John O'Keefe, +1 more
TL;DR: The amnesic syndrome is presented as an extension of the theory to humans and the role of operators in the locale system is examined.
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Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents.:

TL;DR: The sensitivity of this new method in demonstrating retrograde transport is markedly superior to that of the previously described benzidine dihydrochloride method and, as a consequence, many efferent connections of the injection site are also visualized.
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A proposed mechanism of emotion

TL;DR: The following discussion presents some anatomic, clinical and experimental data dealing with the hypothalamus, the gyrus cinguli, the hippocampus and their interconnections, which are proposed as representing theoretically the anatomic basis of the emotions.
Journal ArticleDOI

Spatial memory and hippocampal function.

TL;DR: Rats with damage to the fimbria-fornix were tested for the post-operative retention of a preoperatively learned discrimination on a radial arm maze, suggesting a differential involvement of the hippocampus in working memory as compared to reference memory.
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