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Effect of Clopidogrel on Early Failure of Arteriovenous Fistulas for Hemodialysis

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TLDR
In this article, the Dialysis Access Consortium (DACA) study group presented a study of the Dialysysmosis Access Consortium and its relationships with the following physicians:Laura M. Dember, MDGerald J. Beck, PhDMichael Allon, MDJames A. Delmez, MDBradley S. Dixon, MDArthur Greenberg, MDJonathan Himmelfarb, MDMiguel A. Vazquez, MDJennifer J. Radeva, MSGregory L. Braden, MDT.
Abstract
Laura M. Dember, MDGerald J. Beck, PhDMichael Allon, MDJames A. Delmez, MDBradley S. Dixon, MDArthur Greenberg, MDJonathan Himmelfarb, MDMiguel A. Vazquez, MDJennifer J. Gassman, PhDTom Greene, PhDMilena K. Radeva, MSGregory L. Braden, MDT. Alp Ikizler, MDMichael V. Rocco, MD, MSCEIngemar J. Davidson, MDJames S. Kaufman, MDCatherine M. Meyers, MDJohn W. Kusek, PhDHarold I. Feldman, MD, MSCEfor the Dialysis Access ConsortiumStudy GroupA

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Citations
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Antiplatelet Medications in Hemodialysis Patients: A Systematic Review of Bleeding Rates

TL;DR: Until a clinical trial addresses this in the dialysis population, individual risk stratification taking into account the increased risk of bleeding should be considered before initiating antiplatelet agents, especially in combination therapy.
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Effect of regional versus local anaesthesia on outcome after arteriovenous fistula creation: a randomised controlled trial

TL;DR: Compared with local anaesthesia, BPB significantly improved 3 month primary patency rates for arteriovenous fistula patency in adults undergoing primary radiocephalic or brachial plexus block creation.
Journal ArticleDOI

Therapeutic strategies to combat neointimal hyperplasia in vascular grafts.

TL;DR: The pathophysiologic pathways that underlie the formation of NIH in both vein and synthetic grafts are summarized and current and potential mechanical and molecular approaches under investigation that may limit NIH in vascular grafts is discussed.
Journal ArticleDOI

Achieving the Goal of the Fistula First Breakthrough Initiative for Prevalent Maintenance Hemodialysis Patients

TL;DR: There is a need to decrease regional variation before the CMS goal of 66% prevalent AVF use can be fully realized for US HD facilities, and the national scope of the initiative precludes use of a comparison group.
Journal ArticleDOI

Fistula First Initiative: Historical Impact on Vascular Access Practice Patterns and Influence on Future Vascular Access Care

TL;DR: The evolution of the FFBI should underscore the need for multidisciplinary health teams with a major emphasis placed on “the right access for the right patient” and improving the patient’s overall quality of life.
References
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Journal ArticleDOI

Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease

TL;DR: In this paper, the role and limitations of retrospective investigations of factors possibly associated with the occurrence of a disease are discussed and their relationship to forward-type studies emphasized, and examples of situations in which misleading associations could arise through the use of inappropriate control groups are presented.
Book

Group Sequential Methods with Applications to Clinical Trials

TL;DR: A short history of sequential and group sequential methods can be found in this paper, where the authors present a road map for the application of two-sided tests for comparing two treatments with normal response of known variance.
Journal ArticleDOI

Increasing arteriovenous fistulas in hemodialysis patients: Problems and solutions

TL;DR: Implementing these measures is likely to increase the prevalence of fistulas in any given dialysis unit, however, differences among dialysis units are likely to persist because of differences in gender, race, and co-morbidity mix of the patient population.
Journal ArticleDOI

Hemodialysis vascular access morbidity.

TL;DR: To reduce vascular access-related morbidity, strategies must be developed not only to prevent and detect appropriately early synthetic vascular access dysfunction, but to better identify the patients in a whom radial arteriovenous fistula is a viable clinical option.
Journal ArticleDOI

Aggressive treatment of early fistula failure

TL;DR: If correctable pathology is detected in patients with early fistula failure, the incidence of correctable lesions is relatively high and an aggressive therapeutic approach can be expected to have a high yield.
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