Journal ArticleDOI
Effect of Continuous Positive Airway Pressure and Placebo Treatment on Sympathetic Nervous Activity in Patients With Obstructive Sleep Apnea
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It is concluded that daytime sympathetic nervous activation is greater with more severe sleep apnea, and CPAP treatment diminished the daytime sympathetic activation.About:
This article is published in Chest.The article was published on 2001-09-01. It has received 183 citations till now. The article focuses on the topics: Continuous positive airway pressure & Obstructive sleep apnea.read more
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Reference EntryDOI
Continuous positive airways pressure for obstructive sleep apnoea in adults
Tammie L Giles,Toby J Lasserson,Brian J. Smith,John H. White,John Wright,Christopher J Cates +5 more
TL;DR: CPAP is effective in reducing symptoms of sleepiness and improving quality of life measures in people with moderate and severe obstructive sleep apnoea (OSA).
Journal ArticleDOI
Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities
TL;DR: Large-scale collaborative studies of carefully defined patient populations with obstructive sleep apnoea syndrome, adequately controlled for potential confounders, are needed and research priorities to identify the underlying mechanisms involved are proposed, with a view to identifying novel therapeutic strategies.
Journal ArticleDOI
Practice parameters for the use of continuous and bilevel positive airway pressure devices to treat adult patients with sleep-related breathing disorders.
Clete A. Kushida,Michael R. Littner,Max Hirshkowitz,Timothy I. Morgenthaler,Cathy A. Alessi,Dennis R. Bailey,Brian Boehlecke,Terry Brown,Jack Coleman,Leah Friedman,Sheldon Kapen,Vishesh K. Kapur,Milton Kramer,Teofilo Lee-Chiong,Judith A. Owens,Jeffrey Pancer,Todd J. Swick,Merrill S. Wise +17 more
TL;DR: CPAP is effective for treating OSA and BPAP may be useful in treating some forms of restrictive lung disease or hypoventilation syndromes associated with hypercapnia, and practice parameters for APAP are developed.
Journal ArticleDOI
Evaluation of positive airway pressure treatment for sleep related breathing disorders in adults.
TL;DR: A systematic analysis and grading of peer-reviewed, published clinical studies pertaining to application of PAP treatment in adults and the use of bilevel PAP therapy is reviewed for both patients with OSA and those with other selected nocturnal breathing disorders.
Journal ArticleDOI
The impact of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syndrome: evidence from a meta-analysis of placebo-controlled randomized trials.
Patrick Haentjens,Alain Van Meerhaeghe,A. Moscariello,Sonia De Weerdt,Kris Poppe,Alain Dupont,Brigitte Velkeniers +6 more
TL;DR: Among patients with OSAS, CPAP reduces 24-hour ambulatory MBP, with greater treatment-related reductions in ambulatory blood pressure among patients with a more severe degree of OSAS and a better effective nightly use of the CPAP device.
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Journal ArticleDOI
Sympathetic neural mechanisms in obstructive sleep apnea.
TL;DR: It is concluded that patients with obstructive sleep apnea have high sympathetic activity when awake, with further increases in blood pressure and sympathetic activity during sleep, which are attenuated by treatment with CPAP.
Journal ArticleDOI
Obstructive Sleep Apnea
TL;DR: The nature and consequences of upper-airway obstruction in adults during sleep has evolved considerably over the past two decades, and there is insufficient awareness of sleep apnea among physicians and the public at large.
Journal ArticleDOI
Association of sleep apnoea with myocardial infarction in men
TL;DR: To examine the hypothesis that sleep apnoea is a risk factor for ischaemic heart disease, overnight polysomnography was performed in 101 unselected male survivors of acute myocardial infarction aged less than 66 yr and in 53 male subjects of similar age without evidence of ischaemia heart disease.
Journal ArticleDOI
Augmented resting sympathetic activity in awake patients with obstructive sleep apnea.
TL;DR: It is concluded that neurogenic sympathetic activity as well as circulating plasma NE is increased in patients with OSA, which may reflect a pathophysiologic adaptation to hypoxia and hemodynamic changes occurring at repetitive apneas during sleep.
Journal ArticleDOI
Nocturnal Continuous Positive Airway Pressure Decreases Daytime Sympathetic Traffic in Obstructive Sleep Apnea
Krzysztof Narkiewicz,Masahiko Kato,Bradley G. Phillips,Catherine A. Pesek,Diane E. Davison,Virend K. Somers +5 more
TL;DR: CPAP treatment decreases muscle sympathetic traffic in patients with OSA, and this effect of CPAP is evident only after an extended duration of therapy.