Journal ArticleDOI
Effects of oral contraceptives on vascular endothelium in premenopausal women.
TLDR
Premenopausal women are protected against atherosclerosis by high plasma estrogen levels, which have been suggested to augment endothelial nitric oxide synthesis and to improve endothelial function, and the influence of oral contraceptive use is investigated.About:
This article is published in American Journal of Obstetrics and Gynecology.The article was published on 2000-07-01. It has received 39 citations till now. The article focuses on the topics: Sodium nitroprusside.read more
Citations
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Journal ArticleDOI
Estrogen modulation of endothelial nitric oxide synthase.
Ken L. Chambliss,Philip W. Shaul +1 more
TL;DR: Observations provide evidence for the existence of a steroid receptor fast-action complex, or SRFC, in caveolae in endothelial cells, and serve as excellent paradigms for further elucidation of novel mechanisms of steroid hormone action.
Journal ArticleDOI
Ethinyl Estradiol and 17β-estradiol in Combined Oral Contraceptives: Pharmacokinetics, Pharmacodynamics and Risk Assessment
TL;DR: A brief summary of the pharmacology of EE and E₂, including metabolism, pharmacokinetics and pharmacodynamics, as well as adverse effects of these estrogens are provided.
Journal ArticleDOI
Long-Term Use of Contraceptive Depot Medroxyprogesterone Acetate in Young Women Impairs Arterial Endothelial Function Assessed by Cardiovascular Magnetic Resonance
TL;DR: The vascular effects of long-term contraceptive DMPA in young women is investigated, finding that FMD was reduced in DMPA users compared with controls, and Serum-estradiol levels were measured at both visits.
Journal ArticleDOI
Oral contraceptives improve endothelial function in amenorrheic athletes.
TL;DR: It is concluded that amenorrheic athletes benefit from treatment with OC with respect to endothelial function and some modest alterations in the lipid profile and in markers of inflammation.
Journal ArticleDOI
Endothelial function across an oral contraceptive cycle in women using levonorgestrel and ethinyl estradiol
TL;DR: The results suggest that levonorgestrel may antagonize the activity of ethinyl estradiol, and both the progestin type and estradio dose need to be considered when assessing arterial vascular risk of OCP use in women.
References
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Journal ArticleDOI
The pathogenesis of atherosclerosis: a perspective for the 1990s
TL;DR: The ability to control the expression of genes encoding these molecules and to target specific cell types provides opportunities to develop new diagnostic and therapeutic agents to induce the regression of the lesions and, possibly, to prevent their formation.
Journal ArticleDOI
Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
David S. Celermajer,Keld E. Sørensen,V.M. Gooch,David Spiegelhalter,Owen Miller,Ian D. Sullivan,J.K. Lloyd,John E. Deanfield +7 more
TL;DR: Endothelial dysfunction is present in children and adults with risk factors for atherosclerosis, such as smoking and hypercholesterolaemia, before anatomical evidence of plaque formation in the arteries studied, suggesting this may be an important early event in atherogenesis.
Book
Williams Textbook of Endocrinology
TL;DR: Williams textbook of endocrinology / , Williams textbooks of endocrineology /, کتابخانه دیجیتال جندی اهواز
Journal ArticleDOI
Regulatory functions of the vascular endothelium.
TL;DR: The vascular endothelium, which envelops the circulating blood in a continuous monolayer, is mainly responsible for this function, but over the past 20 years numerous other important functions have been discovered.
Journal ArticleDOI
Patterns of coronary heart disease morbidity and mortality in the sexes: A 26-year follow-up of the Framingham population
Debra J Lerner,William B. Kannel +1 more
TL;DR: A population-based survey assessed sex-specific patterns of coronary heart disease occurring over a 26-year period of time, finding that among subjects ages 35 to 84 years, men have about twice the total incidence of morbidity and mortality of women.