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Efficacy and safety of left atrial appendage closure with WATCHMAN in patients with or without contraindication to oral anticoagulation: 1-Year follow-up outcome data of the EWOLUTION trial.

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TLDR
This method of stroke risk reduction appears to be safe and effective with an ischemic stroke rate as low as 1.1%, even though 73% of patients had a contraindication to and were not using oral anticoagulation.
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This article is published in Heart Rhythm.The article was published on 2017-09-01 and is currently open access. It has received 301 citations till now. The article focuses on the topics: Stroke & Atrial fibrillation.

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Initiation and development of a percutaneous left atrial appendage closure programme: A French centre's experience and literature review.

TL;DR: In this paper , the authors report the experience of a tertiary French centre in percutaneous left atrial appendage closure and discuss the outcomes compared with previously published series, and a retrospective observational cohort study was conducted.
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Left Atrial Appendage Occlusion Strengths and Weaknesses of the Lobe-Only Occluder Concept in Theory and in Practice.

TL;DR: In this article , two main device designs have been used to perform left atrial appendage closure: those that use a pacifier design (lobe + disk) and those that using a plug (single lobe) design.
References
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Journal ArticleDOI

Standardized Bleeding Definitions for Cardiovascular Clinical Trials A Consensus Report From the Bleeding Academic Research Consortium

TL;DR: Bleeding complications have been associated with an increased risk of subsequent adverse outcomes, including MI, stroke, stent thrombosis, and death, in patients with ACS and in those undergoing percutaneous coronary intervention (PCI) as well as in the long-term antithrombotic setting.
Journal ArticleDOI

Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation

TL;DR: Data suggest that left atrial appendage obliteration is a strategy of potential value for stroke prophylaxis in nonrheumatic atrial fibrillation.
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