Efficacy and safety of left atrial appendage closure with WATCHMAN in patients with or without contraindication to oral anticoagulation: 1-Year follow-up outcome data of the EWOLUTION trial.
Lucas V.A. Boersma,Hueseyin Ince,Stephan Kische,Evgeny Pokushalov,Thomas Schmitz,Boris Schmidt,Tommaso Gori,Felix Meincke,Alexey Vladimir Protopopov,Timothy R. Betts,David P. Foley,Horst Sievert,Patrizio Mazzone,Tom De Potter,Elisa Vireca,Kenneth M. Stein,Martin Bergmann +16 more
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TLDR
This method of stroke risk reduction appears to be safe and effective with an ischemic stroke rate as low as 1.1%, even though 73% of patients had a contraindication to and were not using oral anticoagulation.About:
This article is published in Heart Rhythm.The article was published on 2017-09-01 and is currently open access. It has received 301 citations till now. The article focuses on the topics: Stroke & Atrial fibrillation.read more
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Journal ArticleDOI
Left atrial appendage closure in patients with prohibitive anatomy: Insights from PINNACLE FLX.
Christopher R. Ellis,Gregory G. Jackson,Arvindh Kanagasundram,Moussa Mansour,Brad Sutton,Vicki M. Houle,Saibal Kar,Shephal K. Doshi,Jose Osorio +8 more
TL;DR: In this article, the authors evaluated the safety and efficacy of Watchman FLX in patients with a failed Watchman 2.5 attempt or prohibitive left atrial appendage (LAA) anatomy.
Journal ArticleDOI
Left Atrial Appendage Closure in Atrial Fibrillation
Laurent Fauchier,Alexandre Cinaud,François Brigadeau,Antoine Lepillier,Bertrand Pierre,Daniel Gras,Jacques Mansourati,Jean Claude Deharo,Gilles Montalescot,Pascal Defaye +9 more
TL;DR: Transcatheter left atrial appendage closure is an alternative strategy for stroke prevention in atrial fibrillation patients with contraindications for long-term anticoagulant treatment.
Journal ArticleDOI
Percutaneous approaches for retrieval of an embolized or malpositioned left atrial appendage closure device: A multicenter experience.
Muhammad R. Afzal,Christopher R. Ellis,James Gabriels,Mikhael F. El-Chami,Anish K. Amin,Zaher Fanari,David B. Delurgio,Roy M. John,Apoor Patel,Thomas Haldis,Jeffrey A. Goldstein,Steven J. Yakubov,Emile G. Daoud,John D. Hummel +13 more
TL;DR: Retrieval of an embolized or malpositioned WD is feasible, and familiarity with snares and grasping tools can facilitate a successful removal.
Journal ArticleDOI
Indications for Left Atrial Appendage Occlusion in the United States and Associated In-Hospital Outcomes: Results From the NCDR LAAO Registry
TL;DR: The most common procedural indications for Watchman implantation were increased thromboembolic risk, history of major bleeding, and high fall risk, with gastrointestinal bleeding being most common (41.9%) as discussed by the authors .
Journal ArticleDOI
The cessation of oral anticoagulation following left atrial appendage surgery.
Neil Mangrolia,Prakash P Punjabi +1 more
TL;DR: The evidence guiding this management decision is reviewed, and the safety of cessation of oral anticoagulation after surgical closure of the left atrial appendage in patients with a history of atrial fibrillation is reviewed.
References
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2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Paulus Kirchhof,Stefano Benussi,Dipak Kotecha,Anders Ahlsson,Dan Atar,Barbara Casadei,Manuel Castellá,Hans-Christoph Diener,Hein Heidbuchel,Jeroen M.L. Hendriks,Gerhard Hindricks,Antonis S. Manolis,Jonas Oldgren,Bogdan A. Popescu,Ulrich Schotten,Bart P. Van Putte,Panagiotis Vardas,Stefan Agewall,John Camm,Gonzalo Barón Esquivias,Werner Budts,Scipione Carerj,Filip Casselman,Antonio Coca,Raffaele De Caterina,Spiridon Deftereos,Dobromir Dobrev,José M. Ferro,Gerasimos Filippatos,Donna Fitzsimons,Bulent Gorenek,Maxine Guenoun,Stefan H. Hohnloser,Philippe Kolh,Gregory Y.H. Lip,Athanasios J. Manolis,John J.V. McMurray,Piotr Ponikowski,Raphael Rosenhek,Frank Ruschitzka,Irina Savelieva,Sanjay Sharma,Piotr Suwalski,Juan Tamargo,Clare J Taylor,Isabelle C. Van Gelder,Adriaan A. Voors,Stephan Windecker,José Luis Zamorano,Katja Zeppenfeld +49 more
TL;DR: The Task Force for the management of atrial fibrillation of the European Society of Cardiology has been endorsed by the European Stroke Organisation (ESO).
Journal ArticleDOI
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS: The Task Force for the management of atrial fibrillation of the European Society of Cardiology (ESC). Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Endorsed by the European Stroke Organisation (ESO)
Journal ArticleDOI
Standardized Bleeding Definitions for Cardiovascular Clinical Trials A Consensus Report From the Bleeding Academic Research Consortium
Roxana Mehran,Sunil V. Rao,Deepak L. Bhatt,C. Michael Gibson,Adriano Caixeta,John W. Eikelboom,Sanjay Kaul,Stephen D. Wiviott,Venu Menon,Eugenia Nikolsky,Victor L. Serebruany,Marco Valgimigli,Pascal Vranckx,David P. Taggart,Joseph F. Sabik,Donald E. Cutlip,Mitchell W. Krucoff,E. Magnus Ohman,Philippe Gabriel Steg,Harvey D. White +19 more
TL;DR: Bleeding complications have been associated with an increased risk of subsequent adverse outcomes, including MI, stroke, stent thrombosis, and death, in patients with ACS and in those undergoing percutaneous coronary intervention (PCI) as well as in the long-term antithrombotic setting.
Journal ArticleDOI
Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation
TL;DR: Data suggest that left atrial appendage obliteration is a strategy of potential value for stroke prophylaxis in nonrheumatic atrial fibrillation.
Journal ArticleDOI
Prospective Randomized Evaluation of the Watchman Left Atrial Appendage Closure Device in Patients With Atrial Fibrillation Versus Long-Term Warfarin Therapy: The PREVAIL Trial
David R. Holmes,Saibal Kar,Matthew J. Price,Brian Whisenant,Horst Sievert,Shephal K. Doshi,Kenneth C. Huber,Vivek Y. Reddy +7 more
TL;DR: In this trial, LAA occlusion was noninferior to warfarin for ischemic stroke prevention or SE >7 days' post-procedure in patients with NVAF who do not have an absolute contraindication to short-termwarfarin therapy.
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Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
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