Efficacy and safety of left atrial appendage closure with WATCHMAN in patients with or without contraindication to oral anticoagulation: 1-Year follow-up outcome data of the EWOLUTION trial.
Lucas V.A. Boersma,Hueseyin Ince,Stephan Kische,Evgeny Pokushalov,Thomas Schmitz,Boris Schmidt,Tommaso Gori,Felix Meincke,Alexey Vladimir Protopopov,Timothy R. Betts,David P. Foley,Horst Sievert,Patrizio Mazzone,Tom De Potter,Elisa Vireca,Kenneth M. Stein,Martin Bergmann +16 more
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TLDR
This method of stroke risk reduction appears to be safe and effective with an ischemic stroke rate as low as 1.1%, even though 73% of patients had a contraindication to and were not using oral anticoagulation.About:
This article is published in Heart Rhythm.The article was published on 2017-09-01 and is currently open access. It has received 301 citations till now. The article focuses on the topics: Stroke & Atrial fibrillation.read more
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Journal ArticleDOI
Expert Recommendations on Cardiac Computed Tomography for Planning Transcatheter Left Atrial Appendage Occlusion.
Kasper Korsholm,Sergio Berti,Xavier Iriart,Jacqueline Saw,Dee Dee Wang,Hubert Cochet,Danny Hoi Fan Chow,Alberto Clemente,Ole De Backer,Jesper Møller Jensen,Jens Erik Nielsen-Kudsk +10 more
TL;DR: A protocol for the preparation, acquisition, and interpretation of cardiac computed tomographic imaging in pre-procedural planning of left atrial appendage occlusion is provided.
Journal ArticleDOI
Prevalence of extra-appendage thrombosis in non-valvular atrial fibrillation and atrial flutter in patients undergoing cardioversion: a large transoesophageal echo study.
Alberto Cresti,Miguel Angel García-Fernández,Horst Sievert,Patrizio Mazzone,Pasquale Baratta,Marco Solari,Alessia Geyer,Francesco De Sensi,Ugo Limbruno +8 more
TL;DR: Extra- appendage thrombosis is a very rare finding in non-valvular persistent and paroxysmal atrial tachyarrhythmias and, when present, a left appendageThrombus is usually concomitant.
Journal ArticleDOI
Left atrial appendage occlusion with the Amplatzer™ Amulet™ device: full results of the prospective global observational study
David Hildick-Smith,Ulf Landmesser,A. John Camm,Hans-Christoph Diener,Vince Paul,Boris Schmidt,Magnus Settergren,Emmanuel Teiger,Jens Erik Nielsen-Kudsk,Claudio Tondo +9 more
TL;DR: Following LAAO with the Amplatzer Amulet device, the ischaemic stroke rate was reduced by 67% compared to the predicted risk, and patients were discharged on antiplatelet therapy alone.
Journal ArticleDOI
Percutaneous Left Atrial Appendage Closure: Current Devices and Clinical Outcomes.
Lluis Asmarats,Josep Rodés-Cabau +1 more
TL;DR: An updated overview of current transcatheterleft atrial appendage closure devices is provided and the results associated with left atrialappendage closure are reviewed, focusing on procedural and late outcomes, and pointing to future directions.
Journal ArticleDOI
Left Atrial Appendage Occlusion for The Unmet Clinical Needs of Stroke Prevention in Nonvalvular Atrial Fibrillation
TL;DR: A review focuses on the growing literature to put into perspective the risk‐balance ratio of left atrial appendage occlusion and the risk of stroke prevention in patients with nonvalvular atrial fibrillation.
References
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2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Paulus Kirchhof,Stefano Benussi,Dipak Kotecha,Anders Ahlsson,Dan Atar,Barbara Casadei,Manuel Castellá,Hans-Christoph Diener,Hein Heidbuchel,Jeroen M.L. Hendriks,Gerhard Hindricks,Antonis S. Manolis,Jonas Oldgren,Bogdan A. Popescu,Ulrich Schotten,Bart P. Van Putte,Panagiotis Vardas,Stefan Agewall,John Camm,Gonzalo Barón Esquivias,Werner Budts,Scipione Carerj,Filip Casselman,Antonio Coca,Raffaele De Caterina,Spiridon Deftereos,Dobromir Dobrev,José M. Ferro,Gerasimos Filippatos,Donna Fitzsimons,Bulent Gorenek,Maxine Guenoun,Stefan H. Hohnloser,Philippe Kolh,Gregory Y.H. Lip,Athanasios J. Manolis,John J.V. McMurray,Piotr Ponikowski,Raphael Rosenhek,Frank Ruschitzka,Irina Savelieva,Sanjay Sharma,Piotr Suwalski,Juan Tamargo,Clare J Taylor,Isabelle C. Van Gelder,Adriaan A. Voors,Stephan Windecker,José Luis Zamorano,Katja Zeppenfeld +49 more
TL;DR: The Task Force for the management of atrial fibrillation of the European Society of Cardiology has been endorsed by the European Stroke Organisation (ESO).
Journal ArticleDOI
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS: The Task Force for the management of atrial fibrillation of the European Society of Cardiology (ESC). Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Endorsed by the European Stroke Organisation (ESO)
Journal ArticleDOI
Standardized Bleeding Definitions for Cardiovascular Clinical Trials A Consensus Report From the Bleeding Academic Research Consortium
Roxana Mehran,Sunil V. Rao,Deepak L. Bhatt,C. Michael Gibson,Adriano Caixeta,John W. Eikelboom,Sanjay Kaul,Stephen D. Wiviott,Venu Menon,Eugenia Nikolsky,Victor L. Serebruany,Marco Valgimigli,Pascal Vranckx,David P. Taggart,Joseph F. Sabik,Donald E. Cutlip,Mitchell W. Krucoff,E. Magnus Ohman,Philippe Gabriel Steg,Harvey D. White +19 more
TL;DR: Bleeding complications have been associated with an increased risk of subsequent adverse outcomes, including MI, stroke, stent thrombosis, and death, in patients with ACS and in those undergoing percutaneous coronary intervention (PCI) as well as in the long-term antithrombotic setting.
Journal ArticleDOI
Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation
TL;DR: Data suggest that left atrial appendage obliteration is a strategy of potential value for stroke prophylaxis in nonrheumatic atrial fibrillation.
Journal ArticleDOI
Prospective Randomized Evaluation of the Watchman Left Atrial Appendage Closure Device in Patients With Atrial Fibrillation Versus Long-Term Warfarin Therapy: The PREVAIL Trial
David R. Holmes,Saibal Kar,Matthew J. Price,Brian Whisenant,Horst Sievert,Shephal K. Doshi,Kenneth C. Huber,Vivek Y. Reddy +7 more
TL;DR: In this trial, LAA occlusion was noninferior to warfarin for ischemic stroke prevention or SE >7 days' post-procedure in patients with NVAF who do not have an absolute contraindication to short-termwarfarin therapy.
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Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
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