Electrochemical Selenylative Carbannulation of Biaryl Ynones to Seleno-Dibenzocycloheptenones/Spiro[5.5]Trienones.
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TLDR
In this article, a method for the synthesis of structurally diverse seleno-dibenzocyclohepten-5-ones and selenon-spiro[5.5]trienones by selenylative carbannulation of biaryl ynones with diary l diselenide was developed.Abstract:
Electrooxidative-induced synthesis of structurally diverse seleno-dibenzocyclohepten-5-ones and seleno-spiro[5.5]trienones by selenylative carbannulation of biaryl ynones with diaryl diselenide has been developed. The switchable reactivity, intramolecular ortho-annulation or dearomative ipso-annulation, is directed by the substituent present on the ortho-aryl group of aryl-ynone. The prominent features of this method include metal-free, external chemical oxidant-free conditions, and readily accessible substrates.read more
Citations
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K2S2O8/I2-Promoted Electrophilic Selenylative Cyclization To Access Seleno-Benzo[b]azepines.
Zhen Zhang,Shi-Qun Wang,Pengpeng Tan,Xiaowen Gu,Wen-Chan Sun,Chang Liu,Jin‐Chun Chen,Jiazhu Li,Kai-Jin Sun +8 more
TL;DR: A novel and simple organoselenium-involved 7-membered cyclization to access diverse seleno-benzo[b]azepines and large-scale experiment reveal the promising utility of this methodology.
Journal ArticleDOI
Synthesis of Seleno-Dibenzocycloheptenones/Spiro[5.5]Trienones by Radical Cyclization of Biaryl Ynones.
Helen A. Goulart,Ricardo H. Bartz,Thiago J. Peglow,Angelita M. Barcellos,Rodrigo Cervo,Roberta Cargnelutti,Raquel G. Jacob,Eder J. Lenardão,Gelson Perin +8 more
TL;DR: In this paper , an alternative method for the synthesis of seleno-dibenzocycloheptenones and selenon-spiro[5.5]trienones through the radical cyclization of biaryl ynones, using Oxone as a green oxidizing agent.
Journal ArticleDOI
Iron‐Catalyzed Silylation and Spirocyclization of Biaryl‐Ynones: A Radical Cascade Process toward Silylated Spiro[5.5]trienones
TL;DR: In this paper , an iron-catalyzed cascade silyl radical addition/6-exo-trig cyclization/dearomatization of biaryl ynones has been developed.
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Regio- and stereo-selective electrochemical selenoalkylation of alkynes with 1,3-dicarbonyl compounds and diselenides
TL;DR: In this article , a regio-and stereo-selective electrochemical approach for the seleno(monofluoro)alkylation of alkynes with 1,3-dicarbonyl compounds and diselenides has been developed.
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Electrochemical electrophilic bromination/spirocyclization of <i>N</i>-benzyl-acrylamides to brominated 2-azaspiro[4.5]decanes
Mike Riepl,Emmanuel Ifeanyi Ani +1 more
TL;DR: In this paper , an electrochemical electrophilic bromination/spirocyclization of N -benzyl-acrylamides to brominated 2-azaspiro[4.5]decanes with 2-bromoethan-1-ol as the brominating reagent has been developed.
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