Journal ArticleDOI
Enantiodivergent synthesis of (+)- and (−)-isolaurepan
Reads0
Chats0
TLDR
In this paper, the enantiodivergent synthesis of (+)-and (−)-isolaurepan was achieved from a common chiral template easily available from tri-O-acetyl-d -glucal, using as key step a diastereoselective thermal Claisen rearrangement, combined with a ring expansion reaction using trimethylsilyldiazomethane.About:
This article is published in Tetrahedron.The article was published on 2012-11-04. It has received 14 citations till now. The article focuses on the topics: Glucal & Claisen rearrangement.read more
Citations
More filters
Journal ArticleDOI
Homologation Reaction of Ketones with Diazo Compounds
TL;DR: This review covers the addition of diazo compounds to ketones to afford homologated ketones, either in the presence or in the absence of promoters or catalysts, commenting on the complex regiochemistry of the reaction and the nature of the catalysts and promoters.
Journal ArticleDOI
Sulfonyl Hydrazides in Organic Synthesis: A Review of Recent Studies
Journal ArticleDOI
Sulfonyl radical triggered selective iodosulfonylation and bicyclization of 1,6-dienes
Shi-Ping Wu,Dong-Kai Wang,Qing-Qing Kang,Guo-Ping Ge,Hongxing Zheng,Meiling Zhu,Ting Li,Jun-Qi Zhang,Wen-Ting Wei +8 more
TL;DR: In this paper, a sulfonyl radical triggered selective iodosulfonylation and bicyclization of 1,6-dienes has been described for the first time, which provides a unique platform for precise radical cyclization.
Journal ArticleDOI
Stereodivergent routes in organic synthesis: marine natural products, lactones, other natural products, heterocycles and unnatural compounds
TL;DR: Natural products containing five-membered lactones like quercus lactones, muricatacins, goniofufuranones, methylenolactocins and frenolicin B have been synthesized using stereodivergent routes.
Book ChapterDOI
Seven-Membered Rings
Adam G. Meyer,Alex C. Bissember,Christopher J. T. Hyland,Charlotte C. Williams,Monika Szabo,Steven M. Wales,Grace E. O. Constable,Wesley J. Olivier +7 more
TL;DR: The focus of much of the literature has been on aromatic systems containing at least 1 N atom and has often been driven by a desire to prepare these heterocycles in a stereocontrolled fashion, the search for new bioactives, and the synthesis of natural products as mentioned in this paper.
References
More filters
Journal ArticleDOI
Ring closure reactions of bifunctional chain molecules
Journal ArticleDOI
The chemistry and biological function of natural marine toxins.
TL;DR: Structures of 16 ciguatoxin congeners were successfully elucidated by FAB/MS/MS using samples of 5 microg or less and stereochemical assignments were achieved on dinophysistoxin-1, pectenotoxins, yessotoxin, polycavernoside-A, azaspiracid, and prymnesins.