Journal ArticleDOI
Engineering of smart nanoconstructs for delivery of glucagon-like peptide-1 analogs.
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TLDR
In this article, the authors highlight the latest advances in designing smart multifunctional nanoconstructs and engineering targeted and stimuli-responsive nanoassemblies for delivery of GLP-1 receptor agonists.About:
This article is published in International Journal of Pharmaceutics.The article was published on 2021-03-15. It has received 7 citations till now.read more
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Journal ArticleDOI
Methods for preparation of niosomes: A focus on thin-film hydration method.
TL;DR: In this paper, procedures involved in the thin-film hydration method, a commonly used method for the preparation of niosomes, are described in detail, while highlighting precautions that should be considered for consistent and reproducible construction of Niosomes.
Journal ArticleDOI
Methods for preparation of niosomes: A focus on thin-film hydration method
TL;DR: In this article , procedures involved in the thin-film hydration method, a commonly used method for the preparation of niosomes, are described in detail, while highlighting precautions that should be considered for consistent and reproducible construction of Niosomes.
Journal ArticleDOI
Methods for preparation of nanostructured lipid carriers
TL;DR: In this paper , the procedures involved in emulsification-solvent evaporation method, one of the commonly utilized methods for preparation of NLCs, are described in detail.
Journal ArticleDOI
Methods for preparation of nanostructured lipid carriers
TL;DR: In this article, the procedures involved in emulsification-solvent evaporation method, one of the commonly utilized methods for preparation of NLCs, are described in detail.
Journal ArticleDOI
Enhancement of DPP-IV inhibitory activity and the capacity for enabling GLP-1 secretion through RADA16-assisted molecular designed rapeseed peptide nanogels.
TL;DR: The objective was to develop a nanogel strategy to resist the hydrolysis of digestive and intestinal enzymes to enhance the DPP-IV inhibitory activity of RAP1 and RAP2, and stimulate glucagon-like peptide 1 (GLP-1) secretion of R AP2 by a RADA16-assisted molecular design.
References
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Journal ArticleDOI
Global and societal implications of the diabetes epidemic
TL;DR: The prevention of diabetes and control of its micro- and macrovascular complications will require an integrated, international approach if the authors are to see significant reduction in the huge premature morbidity and mortality it causes.
Journal ArticleDOI
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
TL;DR: Clinical trials with the incretin mimetic exenatide and liraglutide show reductions in fasting and postprandial glucose concentrations, and haemoglobin A1c (HbA1c) associated with weight loss, but long-term clinical studies are needed to determine the benefits of targeting the inc retin axis for the treatment of type 2 diabetes.
Journal ArticleDOI
Nano based drug delivery systems: recent developments and future prospects
Jayanta Kumar Patra,Gitishree Das,Leonardo Fernandes Fraceto,Leonardo Fernandes Fraceto,Estefania Vangelie Ramos Campos,Estefania Vangelie Ramos Campos,Maria del Pilar Rodriguez-Torres,Laura Susana Acosta-Torres,Luis A. Diaz-Torres,Renato Grillo,Mallappa Kumara Swamy,Shivesh Sharma,Solomon Habtemariam,Han-Seung Shin +13 more
TL;DR: An updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs and selective diagnosis through disease marker molecules is presented.
Journal ArticleDOI
Biology of Incretins: GLP-1 and GIP
TL;DR: This review focuses on the mechanisms regulating the synthesis, secretion, biological actions, and therapeutic relevance of the incretin peptides glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1).
Journal ArticleDOI
Global aetiology and epidemiology of type 2 diabetes mellitus and its complications.
TL;DR: An updated view of the global epidemiology of type 2 diabetes mellitus, as well as dietary, lifestyle and other risk factors for T2DM and its complications are provided.
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