Journal ArticleDOI
Enhancement of amphetamine-induced locomotor activity and dopamine release in nucleus accumbens following excitotoxic lesions of the hippocampus
Lawrence Stephen Wilkinson,Guy Mittleman,Eduardo Miguel Torres,Trevor Humby,F. S. Hall,Trevor W. Robbins +5 more
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TLDR
This study tested the hypothesis that the hippocampus modulates dopamine-dependent function of the nucleus accumbens using behavioural and neurochemical evidence and functional interactions between the hippocampus and nucleus Accumbens involving the control of mesolimbic dopamine release.About:
This article is published in Behavioural Brain Research.The article was published on 1993-06-30. It has received 116 citations till now. The article focuses on the topics: Nucleus accumbens & Dopamine.read more
Citations
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Journal ArticleDOI
A neurobiological basis for substance abuse comorbidity in schizophrenia.
TL;DR: It is hypothesized that schizophrenic patients may have a predilection for addictive behavior as a primary disease symptom in parallel to, and in many, cases independent from, their other symptoms.
Journal ArticleDOI
Ventral hippocampal lesions affect anxiety but not spatial learning.
David M. Bannerman,Matthew S. Grubb,Robert M. J. Deacon,Benjamin K. Yee,Joram Feldon,J. N. P. Rawlins +5 more
TL;DR: The results suggest that the ventral hippocampus may play a role in a brain system (or systems) associated with fear and/or anxiety, and provide further evidence for a distinct specialisation of function along the septotemporal axis of the hippocampus.
Journal ArticleDOI
Double dissociation of function within the hippocampus: a comparison of dorsal, ventral, and complete hippocampal cytotoxic lesions.
David M. Bannerman,Benjamin K. Yee,Mark Andrew Good,M. J. Heupel,Susan D. Iversen,J. N. P. Rawlins +5 more
TL;DR: Rats with complete cytotoxic hippocampal lesions exhibited spatial memory impairments in both the water maze and elevated T maze and were less efficient on a nonspatial, differential reinforcement of low rates (DRL) task.
Journal ArticleDOI
Double dissociation of function within the hippocampus: spatial memory and hyponeophagia.
TL;DR: Results show a double dissociation between dorsal and ventral hippocampal lesions (hyponeophagia vs. spatial memory), suggesting differentiation of function along the septotemporal axis of this structure.
Journal ArticleDOI
Stress, depression and the mesolimbic dopamine system.
TL;DR: Re-evaluating results obtained from animal models of depression based on experimental stressors in the light of the most recent data indicate a strong relationship between these neurochemical and behavioural effects and suggest that they could model stress-induced expression and exacerbation of some depressive symptoms.
References
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The Rat Brain in Stereotaxic Coordinates
George Paxinos,Charles Watson +1 more
TL;DR: This paper presents a meta-analyses of the determinants of earthquake-triggered landsliding in the Czech Republic over a period of 18 months in order to establish a probabilistic framework for estimating the intensity of the earthquake.
Journal ArticleDOI
Specificity in the projection patterns of accumbal core and shell in the rat.
TL;DR: The efferent projections of the core and shell areas of the nucleus accumbens were studied with a combination of anterograde and retrograde tract-tracing methods, including Phaseolus vulgaris-leucoagglutinin, horseradish peroxidase and fluorescent tracers.
Journal ArticleDOI
Mesocorticolimbic dopaminergic network: functional and regulatory roles
M. Le Moal,H. Simon +1 more
TL;DR: Article de synthese sur le reseau dopaminergique mesocorticolimbique chez les mammiferes dans le cerveau en fonction du comportement and en f onction de l'individu.
Journal ArticleDOI
Organization of the projections from the subiculum to the ventral striatum in the rat. A study using anterograde transport of Phaseolus vulgaris leucoagglutinin.
TL;DR: It appears that not only the entire nucleus accumbens, part of the so-called ventral striatum, receives fibres from the subiculum, but that the hippocampal projection area in the striatum includes also the most medial, ventral, rostral and caudal parts of the caudate-putamen complex.
Journal ArticleDOI
Selective 60HDA-induced destruction of mesolimbic dopamine neurons: Abolition of psychostimulant-induced locomotor activity in rats
Peter H. Kelly,Susan D. Iversen +1 more
TL;DR: The protection by DMI of noradrenergic neurons from the toxic effects of 60HDA is evidence that 60H DA, as used here, destroys catecholamine neurons mainly by an uptake-dependent specific mechanism.
Related Papers (5)
The distribution of the projection from the hippocampal formation to the nucleus accumbens in the rat: An anterograde and retrograde-horseradish peroxidase study
A.E. Kelley,Valerie B. Domesick +1 more