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Enzymology and Molecular Biology of Aflatoxin Biosynthesis.

Robert E. Minto, +1 more
- 10 Nov 1997 - 
- Vol. 97, Iss: 7, pp 2537-2556
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This article is published in Chemical Reviews.The article was published on 1997-11-10. It has received 237 citations till now.

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Clustered pathway genes in aflatoxin biosynthesis.

TL;DR: Aflatoxins, a group of polyketide-derived furanocoumarins, are the most toxic and carcinogenic compounds among the known mycotoxins and there are only four major aflatoxINS, B1, B2, G1, and G2.
Journal ArticleDOI

Regulation of Secondary Metabolism in Filamentous Fungi

TL;DR: The current understanding of the genetic regulation of secondary metabolism from clustering of biosynthetic genes to global regulators balancing growth, sporulation, and secondary metabolite production in selected fungi is presented with emphasis on regulation of metabolites of agricultural concern.
Journal ArticleDOI

Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secrets

TL;DR: The current state of knowledge regarding the links between gene sequence, protein architecture and biosynthetic programming for fungal polyketide synthases is outlined.
References
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p53 mutations in human cancers

TL;DR: The p53 mutational spectrum differs among cancers of the colon, lung, esophagus, breast, liver, brain, reticuloendothelial tissues, and hemopoietic tissues as mentioned in this paper.
Journal ArticleDOI

Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

TL;DR: Allelic deletions from chromosome 17p and mutations of the p53 gene found in 50% of primary HCCs from southern Africa are reported, with four of five mutations detected were G → T substitutions, with clusters at codon 249.
Book

Handbook of toxic fungal metabolites

TL;DR: This handbook of toxic fungal metabolites that can be your partner is this proper and easy way to gain knowledge about this life, about the world.
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Molecular Genetics of Polyketides and Its Comparison to Fatty Acid Biosynthesis

TL;DR: The structure of the biotechnology of POL YKETIDE SYNTHESIS is studied to understand the role of polyketides in plant growth and their role in the environment.
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