Journal ArticleDOI
Etiology of squamous cell carcinoma of the penis.
Reads0
Chats0
TLDR
The evidence on risk factors for penile cancer suggests that preventive measures that could be considered include prevention of phimosis, treatment of chronic inflammatory conditions, limiting PUVA treatment, smoking cessation and prophylactic prevention of HPV infection.Abstract:
Objective: To review the epidemiology of invasive cancer of the penis based on scientific publications identified by a Medline search from 1966-2000 for the keywords penis/penile, cancer/carcinoma and risk as well as the cited references in the identified papers. Results: Strong risk factors (OR >10) identified by case-control studies included phimosis, chronic inflammatory conditions such as balanopostitis and lichen sclerosus et atrophicus and treatment with psoralen and ultraviolet A photo\chemotheraphy (PUVA). A consistent association was found between penile cancer and smoking that was dose-dependent and not explained by investigated confounding factors such as sexual history. Sexual history and self-reported history of condyloma were associated with a 3-5-fold increased penile cancer risk. Cervical cancer in the wife was not consistently associated with cancer of the penis in the husband. Circumcision was associated with penile cancer risk in ecological studies. In a case-control study, circumcision...read more
Citations
More filters
Journal ArticleDOI
Clinical practice guidelines in oncology
William J. Gradishar,Benjamin O. Anderson,Ron Balassanian,Sarah L. Blair,Harold J. Burstein,Amy E. Cyr,Anthony D. Elias,William B. Farrar,Andres Forero,Sharon H. Giordano,Matthew P. Goetz,Lori J. Goldstein,Steven J. Isakoff,Janice A. Lyons,P. Kelly Marcom,Ingrid A. Mayer,Beryl McCormick,Meena S. Moran,Ruth O'Regan,Sameer A. Patel,Lori J. Pierce,Elizabeth C. Reed,Kilian E. Salerno,Lee S. Schwartzberg,Amy Sitapati,Karen L. Smith,Mary Lou Smith,Hatem Soliman,George Somlo,Melinda L. Telli,John H. Ward,Rashmi Kumar,Dorothy A. Shead +32 more
TL;DR: This manuscript focuses on the NCCN Guidelines Panel recommendations for the workup, primary treatment, risk reduction strategies, and surveillance specific to DCIS.
Journal ArticleDOI
EAU Penile Cancer Guidelines 2009
Giorgio Pizzocaro,Ferran Algaba,Simon Horenblas,Eduard Solsona,S. Tana,Hein Van Der Poel,Nicholas A. Watkin +6 more
TL;DR: Improvements in the management of SCC of the penis are reflected in changes in the guidelines, but the rarity of the disease precluded randomized studies, leading to low level of evidence and grade of recommendation.
Journal ArticleDOI
Human papillomavirus: epidemiology and public health.
Mark Schiffman,Philip E. Castle +1 more
TL;DR: Clinicians and patients will need to shift discussions of the mildly abnormal Papanicolaou test to consideration of HPV infection as a common sexually transmitted infection that rarely causes cervical cancer.
Journal ArticleDOI
Penile cancer: epidemiology, pathogenesis and prevention
Maaike C G Bleeker,Daniëlle A.M. Heideman,Peter J.F. Snijders,Simon Horenblas,Joakim Dillner,Chris J.L.M. Meijer +5 more
TL;DR: A systematic review of the literature evaluating penile carcinogenesis, risk factors and molecular mechanisms involved presents an overview of the different histologically and clinically identified precursor lesions of penile cancer and discusses the molecular pathogenesis, including the role of HPV.
References
More filters
Book
Cancer Incidence in Five Continents
Freddie Bray,J. Ferlay,Mathieu Laversanne,David H. Brewster,C. Gombe Mbalawa,B. Kohler,Marion Piñeros,Eva Steliarova-Foucher,Rajaraman Swaminathan,Sebastien Antoni,Isabelle Soerjomataram,David Forman +11 more
TL;DR: The aim of this study was to establish a database of histological groups and to provide a level of consistency and quality of data that could be applied in the design of future registries.
Journal ArticleDOI
History of Circumcision, Medical Conditions, and Sexual Activity and Risk of Penile Cancer
C. Maden,Karen J. Sherman,Anna Marie Beckmann,T. G. Hislop,Chong-Ze Teh,Rhoda Ashley,J. R. Daling +6 more
TL;DR: The results suggest that the absence of neonatal circumcision and potential resulting complications are associated with penile cancer, and medical conditions of the penis, sexual activity, infection with HPV, and smoking may increase the risk forPenile cancer.
Journal ArticleDOI
High prevalence of papillomavirus-associated penile intraepithelial neoplasia in sexual partners of women with cervical intraepithelial neoplasia.
TL;DR: The concept that cervical carcinomas and precancerous lesions in women may be associated with genital papillomavirus infection in their male sexual partners is supported.
Related Papers (5)
Penile cancer: importance of circumcision, human papillomavirus and smoking in in situ and invasive disease.
Janet R. Daling,Janet R. Daling,Margaret M. Madeleine,Margaret M. Madeleine,Lisa G. Johnson,Stephen M. Schwartz,Katherine A. Shera,Michelle A. Wurscher,Joseph J. Carter,Peggy L. Porter,Peggy L. Porter,Denise A. Galloway,Denise A. Galloway,James K. McDougall,James K. McDougall,John N. Krieger,John N. Krieger +16 more