Journal ArticleDOI
Evaluation of Antineoplastic Drug Exposure of Health Care Workers at Three University-Based US Cancer Centers
Thomas H. Connor,D. Gayle DeBord,Jack R. Pretty,Marc Oliver,Tracy Roth,Peter S.J. Lees,Edward F. Krieg,Bonnie Rogers,Carmen P. Escalante,Christine A. Toennis,John C. Clark,Belinda C. Johnson,Melissa A. McDiarmid +12 more
TLDR
Despite following recommended safe-handling practices, workplace contamination with antineoplastic drugs in pharmacy and nursing areas continues at these locations.Abstract:
Objective:This study evaluated health care worker exposure to antineoplastic drugs.Methods:A cross-sectional study examined environmental samples from pharmacy and nursing areas. A 6-week diary documented tasks involving those drugs. Urine was analyzed for two specific drugs, and blood samples wereread more
Citations
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Analysis of anticancer drugs: a review.
Susanne Nussbaumer,Pascal Bonnabry,Pascal Bonnabry,Jean-Luc Veuthey,Sandrine Fleury-Souverain +4 more
TL;DR: In this review, an overview of reported analytical methods for the determination of the most commonly used anticancer drugs is given.
Journal ArticleDOI
Occupational exposures among nurses and risk of spontaneous abortion
Christina C. Lawson,Carissa M. Rocheleau,Elizabeth A. Whelan,Eileen Lividoti Hibert,Barbara Grajewski,Donna Spiegelman,Janet W. Rich-Edwards +6 more
TL;DR: This study suggests that certain occupational exposures common to nurses are related to risks of spontaneous abortion.
Journal ArticleDOI
ASHP Guidelines on Handling Hazardous Drugs
Luci A. Power,Joseph W. Coyne +1 more
TL;DR: ASHP published its first guidance on hazardous drugs (HDs) in 1983 as part of the 1983–84 ASHP Practice Spotlight: Safe Handling of Cytotoxic Drugs and this was followed by technical assistance bulletins in 1985 and 1990 and the ASHP Guidelines on Handling Hazardous Drugs in 2006.
Journal ArticleDOI
Reproductive Health Risks Associated with Occupational Exposures to Antineoplastic Drugs in Health Care Settings: A Review of the Evidence
TL;DR: Occupational exposure to antineoplastic drugs seems to raise the risk of both congenital malformations and miscarriage and health care workers with long-term, low-level occupational exposure to these drugs also seem to have an increased risk of adverse reproductive outcomes.
Journal ArticleDOI
Chromosome 5 and 7 abnormalities in oncology personnel handling anticancer drugs.
TL;DR: Biologically important exposure to genotoxic drugs is apparently occurring in oncology work settings despite reported use of safety practices.
References
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IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
TL;DR: This timely monograph is a distillation of knowledge of hepatitis B, C and D, based on a review of 1000 studies by a small group of scientists, and it is concluded that hepatitis D virus cannot be classified as a human carcinogen.
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Libri Ricevuti: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
Journal ArticleDOI
Annual Report to the Nation on the status of cancer, 1973–1999, featuring implications of age and aging on U.S. cancer burden
Brenda K. Edwards,Holly L. Howe,Lynn A. G. Ries,Michael J. Thun,Harry M. Rosenberg,Rosemary Yancik,Phyllis A. Wingo,Ahmedin Jemal,Ellen G. Feigal +8 more
TL;DR: This year's report contained a special feature focusing on implications of age and aging on the U.S. cancer burden.
Journal ArticleDOI
Occupational exposure to antineoplastic agents at several departments in a hospital. Environmental contamination and excretion of cyclophosphamide and ifosfamide in urine of exposed workers.
TL;DR: The occupational exposure to cyclophosphamide (CP), ifosfamide (IF), 5-fluorouracil (5FU), and methotrexate (MTX) of 25 pharmacy technicians and nurses from four departments of a hospital was investigated as discussed by the authors.
Journal ArticleDOI
Preventing Occupational Exposures to Antineoplastic Drugs in Health Care Settings
TL;DR: The toxicity of antineoplastic drugs has been well known since they were introduced in the 1940s as mentioned in this paper, and many safety provisions were advanced to reduce worker exposure in the 1980s, but recent studies have shown that workers continue to be exposed to these drugs despite safety policy improvements.