Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score)
David J. Hunter,Ali Guermazi,Grace H. Lo,Grace H. Lo,Andrew J. Grainger,Philip G. Conaghan,Robert M. Boudreau,Frank W. Roemer,Frank W. Roemer +8 more
TLDR
The iteratively developed magnetic resonance imaging Osteoarthritis Knee Score shows very good to excellent reliability for the large majority of features assessed and further iterative development and research will include assessment of its validation and responsiveness.About:
This article is published in Osteoarthritis and Cartilage.The article was published on 2011-08-01 and is currently open access. It has received 677 citations till now. The article focuses on the topics: Cohen's kappa & Reliability (statistics).read more
Citations
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Epidemiology of OA
Tuhina Neogi,Yuqing Zhang +1 more
TL;DR: Risk factors for OA include a number of person-level factors, such as age, sex, obesity, and genetics, as well as joint-specific factors that are likely reflective of abnormal loading of the joints.
Journal ArticleDOI
Animal models of osteoarthritis: classification, update, and measurement of outcomes.
TL;DR: This review summarizes the current understanding of the disease pathogenesis, invasive and non-invasive animal models, imaging modalities, and pain assessment techniques in the animals.
Journal ArticleDOI
Meniscus pathology, osteoarthritis and the treatment controversy
TL;DR: Conservative management of patients with knee pain and a degenerative meniscal tear should be considered as a first-line therapy before surgical treatment is contemplated, and the possibility of an increased risk of OA if functional meniscal tissue is removed cannot be overlooked.
Journal ArticleDOI
Synovitis in knee osteoarthritis: a precursor of disease?
I. Atukorala,C.K. Kwoh,Ali Guermazi,Frank W. Roemer,Robert M. Boudreau,Michael J. Hannon,David J. Hunter +6 more
TL;DR: Effusion- synovitis and Hoffa-synovitis strongly predicted the development of iROA in persons with ROA in this nested case–control study.
Journal ArticleDOI
Recent advances in osteoarthritis imaging—the Osteoarthritis Initiative
TL;DR: The rationale and design of the OAI and its cohort are described, imaging protocols and image analyses completed to date are discussed, and published methodological and applied imaging research that has emerged from OAI pilot studies and OAI data releases are described.
References
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The measurement of observer agreement for categorical data
J. R. Landis,Gary G. Koch +1 more
TL;DR: A general statistical methodology for the analysis of multivariate categorical data arising from observer reliability studies is presented and tests for interobserver bias are presented in terms of first-order marginal homogeneity and measures of interob server agreement are developed as generalized kappa-type statistics.
Journal ArticleDOI
Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis
Charles Peterfy,Ali Guermazi,S. Zaim,P. F. J. Tirman,Y. Miaux,Daniel K. White,M. Kothari,Ying Lu,Kenneth H. Fye,S Zhao,Harry K. Genant +10 more
TL;DR: The WORMS method provides multi-feature, whole-organ assessment of the knee in OA using conventional MR images, and shows high inter-observer agreement among trained readers, and may be useful in epidemiological studies and clinical trials of OA.
Journal ArticleDOI
Atlas of individual radiographic features in osteoarthritis, revised
Roy D. Altman,Garry E. Gold +1 more
TL;DR: An updated atlas of radiographic images was produced to assist in grading individual radiographic features of the hand, hip and knee for clinicians and for use in clinical trials.
Journal Article
Atlas of individual radiographic features in osteoarthritis
TL;DR: Radiographs of the hand, hip and knee were screened for evidence of osteoarthritis (OA) and a resultant atlas is offered as an updated guide to standardize interpretation of radiographs prior to and during clinical trials.
Journal ArticleDOI
Incidental meniscal findings on knee MRI in middle-aged and elderly persons
Martin Englund,Ali Guermazi,Daniel Gale,David J. Hunter,Piran Aliabadi,Margaret Clancy,David T. Felson +6 more
TL;DR: Investigative meniscal findings on MRI of the knee are common in the general population and increase with increasing age, and among persons with radiographic evidence of osteoarthritis, the prevalence of a meniscal tear was 63% among those with knee pain, aching, or stiffness on most days and 60% amongst those without these symptoms.
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Roy D. Altman,E. Asch,Daniel Bloch,Giles G. Bole,David G. Borenstein,Kenneth D. Brandt,Wallace C. Christy,Cooke Td,Robert A. Greenwald,Marc C. Hochberg,David S. Howell,David L. Kaplan,William J. Koopman,Selden Longley,Henry J. Mankin,Dennis J. McShane,Thomas A. Medsger,Robert F. Meenan,William M. Mikkelsen,Roland W. Moskowitz,William A. Murphy,B. Rothschild,Mark R. Segal,Leon Sokoloff,Frederick Wolfe +24 more