Journal ArticleDOI
Ferrous Sulfate Reduces Thyroxine Efficacy in Patients with Hypothyroidism
TLDR
Simultaneous ingestion of ferrous sulfate and thyroxine causes a variable reduction in thyroxin efficacy that is clinically significant in some patients.Abstract:
▪Objective:To determine whether simultaneous ingestion of ferrous sulfate and thyroxine reduces the efficacy of thyroid hormone in patients with primary hypothyroidism. ▪Design:Uncontrolle...read more
Citations
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Journal ArticleDOI
Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement
Jacqueline Jonklaas,Antonio C. Bianco,Andrew J. Bauer,Kenneth D. Burman,Anne R. Cappola,Francesco S. Celi,David S. Cooper,Brian W. Kim,Robin P. Peeters,M. Sara Rosenthal,Anna M. Sawka +10 more
TL;DR: It is concluded that levothyroxine should remain the standard of care for treating hypothyroidism and no consistently strong evidence for the superiority of alternative preparations is found.
Journal ArticleDOI
Drugs in Pregnancy
TL;DR: For example, this article found that most drugs that appear in the Physicians' Desk Reference and similar sources contain statements such as, “Use in pregnancy is not recommended unless the potential benefits justify the potential risks to the fetus.
Journal ArticleDOI
Drugs and Thyroid Function
Martin I. Surks,Rubens Sievert +1 more
TL;DR: Testing of thyroid function is common in clinical practice, and many patients who are tested, including those who have or are receiving treatment for thyroid disease, take medications that may affect thyroid function.
Journal ArticleDOI
Levothyroxine Therapy in Patients with Thyroid Disease
TL;DR: For some patients with nodular thyroid disease, conflicting or insufficient data may not allow an unequivocal consensus recommendation, and in such circumstances, the existing evidence is reviewed and a rational strategy for treatment is provided.
Book ChapterDOI
Disorders of the Thyroid Gland
TL;DR: The thyroid gland produces two related hormones, thyroid hormone (T4) and iodothyronine (T3), acting through nuclear receptors, these hormones play a critical role in cell differentiation during development and help maintain thermogenic and metabolic homeostasis in the adult as mentioned in this paper.
References
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Journal ArticleDOI
Interference of iron with the absorption of tetracyclines in man.
TL;DR: Ferrous sulphate administered together with tetracycline and three of its derivatives—oxytetracy Cline, methacyclines, and doxycycline—was found seriously to impair the absorption of these antibiotics.
Journal ArticleDOI
Iron supplements : a common cause of drug interactions
N. R. C. Campbell,B. B. Hasinoff +1 more
TL;DR: A large number of other important and commonly used drugs such as thyroxine, captopril and folic acid have been demonstrated to form stable complexes with iron.
Journal ArticleDOI
Clinical and chemical interactions between iron preparations and ciprofloxacin.
TL;DR: Ciprofloxacin seems to bind to ferric ion in a ratio of 3:1 by interacting with the 4-keto and 3-carboxyl groups on cipro FLXacin, which is probably the cause of the reduction in ciprafloxACin bioavailability in the presence of iron.
Journal ArticleDOI
Reduction in oral penicillamine absorption by food, antacid, and ferrous sulfate
TL;DR: There were good correlations between urinary recovery of total penicillamine and its oxidized metabolites, between urinary copper excretion and the peniillamine plasma concentration AUCs, and between urinary recoveries and thePenicillamines availability is very susceptible to interactions with other substances.
Journal ArticleDOI
Monitoring Therapy in Patients Taking Levothyroxine
TL;DR: Current evidence suggests that the sensitive thyrotropin test should be used to monitor therapy, and adequate long-term studies are needed to determine the role of biochemical testing in monitoring therapy.