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Book ChapterDOI

Disorders of the Thyroid Gland

Phillip K. Pellitteri, +2 more
- pp 1735-1749
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TLDR
The thyroid gland produces two related hormones, thyroid hormone (T4) and iodothyronine (T3), acting through nuclear receptors, these hormones play a critical role in cell differentiation during development and help maintain thermogenic and metabolic homeostasis in the adult as mentioned in this paper.
Abstract
J. Larry Jameson Anthony P. Weetman The thyroid gland produces two related hormones, thyroxine (T4) and tr i iodothyronine (T3) (Fig. 320-1). Acting through nuclear receptors, these hormones play a crit ical role in cell differentiation during development and help maintain thermogenic and metabolic homeostasis in the adult. Disorders of the thyroid gland result primari ly from autoimmune processes that either stimulate the overproduction of thyroid hormones ( thyrotoxicosis) or cause glandular destruction and hormone deficiency (hypothyroidism). In addit ion, benign nodules and various forms of thyroid cancer are relatively common and amenable to detection by physical examination.

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Citations
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Journal ArticleDOI

Thyrotoxicosis and Thyroid Storm

TL;DR: This multidrug, therapeutic approach uses thionamides, iodine, beta-adrenergic receptor antagonists, corticosteroids in certain circumstances, and supportive therapy.
Journal ArticleDOI

Physiology and pathophysiology of respiratory mucosa of the nose and the paranasal sinuses

TL;DR: The pathophysiologies of different subtypes of non-allergic rhinitis are outlined together with treatment recommendations and Basics of endonasal cleaning including mucociliary clearance and nasal reflexes, as well as defence mechanisms are explained.
References
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Journal ArticleDOI

Serum TSH, T4, and Thyroid Antibodies in the United States Population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)

TL;DR: TSH and the prevalence of antithyroid antibodies are greater in females, increase with age, and are more in whites and Mexican Americans than in blacks, which needs more research to relate these findings to clinical status.
Journal ArticleDOI

The Colorado Thyroid Disease Prevalence Study

TL;DR: The results confirm that thyroid dysfunction is common, may often go undetected, and may be associated with adverse health outcomes that can be avoided by serum TSH measurement.
Journal ArticleDOI

The spectrum of thyroid disease in a community: the whickham survey

TL;DR: TSH levels above 6 mu/1 were shown to reflect a significant lowering of circulating thyroxine levels and showed a strong association with thyroid antibodies in both sexes, independent of age.
Journal ArticleDOI

Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child.

TL;DR: Undiagnosed hypothyroidism in pregnant women may adversely affect their fetuses; therefore, screening for thyroid deficiency during pregnancy may be warranted.