Journal ArticleDOI
Drugs in Pregnancy
TLDR
For example, this article found that most drugs that appear in the Physicians' Desk Reference and similar sources contain statements such as, “Use in pregnancy is not recommended unless the potential benefits justify the potential risks to the fetus.Abstract:
Before marketing a new drug, the manufacturer almost never tests the product in pregnant women to determine its effects on the fetus. Consequently, most drugs are not labeled for use during pregnancy. Typically, descriptions of drugs that appear in the Physicians' Desk Reference and similar sources contain statements such as, “Use in pregnancy is not recommended unless the potential benefits justify the potential risks to the fetus.” Since the risk has been adequately established for only a few drugs, physicians caring for pregnant women have very little information to help them decide whether the potential benefits to the mother outweigh . . .read more
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The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Special situations
Gert Van Assche,Axel Dignass,Walter Reinisch,C. Janneke van der Woude,Andreas Sturm,Martine De Vos,Mario Guslandi,Bas Oldenburg,Iris Dotan,Philippe Marteau,Alessandro Ardizzone,Daniel C. Baumgart,Geert R. D'Haens,Paolo Gionchetti,Francisco Portela,Boris Vucelić,Johan D. Söderholm,Johanna C. Escher,Sibylle Koletzko,Kaija-Leena Kolho,Milan Lukas,Christian Mottet,Herbert Tilg,Severine Vermeire,F. Carbonnel,Andrew T. Cole,Gottfried Novacek,Max Reinshagen,Epameinondas V. Tsianos,Klaus Herrlinger,Yoram Bouhnik,Ralf Kiesslich,Eduard F. Stange,Simon Travis,James O. Lindsay +34 more
TL;DR: The aim of this Consensus was therefore critically to evaluate the optimal strategies for the management of post-operative recurrence in CD.
Guidelines on Urological Infections
Magnus Grabe,Riccardo Bartoletti,T. Tony Cai,Béla Köves,Peter Tenke,Florian M.E. Wagenlehner,Björn Wullt +6 more
TL;DR: It is essential to limit the use of antibiotics in general and fluoroquinolones and cephalosporins in particular, especially in uncomplicated infections and asymptomatic bacteriuria.
Journal ArticleDOI
Silica and titanium dioxide nanoparticles cause pregnancy complications in mice.
Kohei Yamashita,Yasuo Yoshioka,Kazuma Higashisaka,Kazuya Mimura,Yuki Morishita,Masatoshi Nozaki,Tokuyuki Yoshida,Toshinobu Ogura,Hiromi Nabeshi,Kazuya Nagano,Yasuhiro Abe,Haruhiko Kamada,Youko Monobe,Takayoshi Imazawa,Hisae Aoshima,Kiyoshi Shishido,Yuichi Kawai,Tadanori Mayumi,Shin-ichi Tsunoda,Norio Itoh,Tomoaki Yoshikawa,Itaru Yanagihara,Shigeru Saito,Yasuo Tsutsumi +23 more
TL;DR: In this paper, the authors showed that nanoparticles with diameters of 70 nm and 35 nm can cause pregnancy complications when injected intravenously into pregnant mice, and that these detrimental effects are linked to structural and functional abnormalities in the placenta on the maternal side, and are abolished when the surfaces of the silica nanoparticles are modified with carboxyl and amine groups.
Journal ArticleDOI
European evidence based consensus on the diagnosis and management of Crohn's disease: special situations.
R. Caprilli,Miquel A. Gassull,Johanna C. Escher,Gabriele Moser,Pia Munkholm,Alastair Forbes,Daan W. Hommes,H. Lochs,Erika Angelucci,A. Cocco,Boris Vucelić,Hans Hildebrand,Sanja Kolaček,L. Riis,Milan Lukas,R. De Franchis,M. Hamilton,G. Jantschek,Pierre Michetti,Colm O'Morain,M. M. Anwar,J. L. Freitas,Ioannis A. Mouzas,Filip Baert,Rod Mitchell,Christopher J. Hawkey +25 more
TL;DR: The third section of the European Crohn's and Colitis Organisation (ECCO) Consensus on the management of Crohn disease concerns postoperative recurrence, fistulating disease, paediatrics, pregnancy, psychosomatics, extraintestinal manifestations, and alternative therapy.
Journal ArticleDOI
The treatment of restless legs syndrome and periodic limb movement disorder. An American Academy of Sleep Medicine Review.
Wayne A. Hening,Richard P. Allen,Christopher J. Earley,Clete A. Kushida,Daniel L. Picchietti,Michael H. Silber +5 more
TL;DR: A task force consisting of six authors reviewed the published literature on the therapy of the restless legs syndrome or periodic limb movements in sleep available in indices through April, 1998 and selected the 45 articles for detailed review which presented original investigations of therapeutic impact and met minimal standards.
References
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Journal ArticleDOI
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Journal ArticleDOI
Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation
Andrew E. Czeizel,István Dudás +1 more
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