Journal ArticleDOI
First Report of Genotyping of Toxoplasma gondii in Free-Living Microtus fortis in Northeastern China
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TLDR
The results suggest that the Type I and ToxoDB Genotype no. 9 could be a potential risk factor for transmission through the reed vole in this region.Abstract:
Toxoplasma gondii is an intracellular protozoan parasite which imperils the health of almost all warm-blooded animals, including humans The objective of this study was to determine genetic characterization of T gondii in free-living Microtus fortis (reed vole) in Jilin province, northeastern China A total of 104 DNA samples, 74 from Gongzhuling and 30 from Baicheng, were extracted from lung tissues of M fortis, and 56 (538%) of them were positive for T gondii by semi-nested polymerase chain reaction of the B1 gene These positive DNA samples were typed at 10 genetic markers including SAG1, 5′- and 3′-SAG2, alternative SAG2, BUTB, GRA6, L358, PK1, c22-8, c29-2, and Apico Four samples were successfully genotyped at all genetic loci and grouped to 2 distinct genotypes; 2 samples belonged to ToxoDB Genotype no 10 (Type I) and the other 2 presented ToxoDB Genotype no 9 (http://toxodborg/toxo/); 4 samples were genotyped at 8 genetic loci, in which 2 samples belonged to ToxoDB Genotype no 10read more
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Geographical distribution of Toxoplasma gondii genotypes in Asia: A link with neighboring continents.
Patcharee Chaichan,Aurélien Mercier,Lokman Galal,Aongart Mahittikorn,Frédéric Ariey,Serge Morand,Farid Boumediene,Ruenruetai Udonsom,Azra Hamidović,Jean-Benjamin Murat,Yaowalark Sukthana,Marie-Laure Dardé +11 more
TL;DR: Although there are some indications of a genetic population structure in Southeast Asian countries different from the rest of Asia, more studies in this tropical part of Asia will be necessary for a region which represent as well as Africa one of the missing links of the T. gondii genetic diversity.
Journal ArticleDOI
Sixty Years (1957-2017) of Research on Toxoplasmosis in China-An Overview.
TL;DR: This review summarizes the major progress made by Chinese scientists over the last 60 years, and gives their perspectives on what should be done in the near future.
Journal ArticleDOI
Variation detection based on next-generation sequencing of type Chinese 1 strains of Toxoplasma gondii with different virulence from China
Weisheng Cheng,Fang Liu,Man Li,Xiaodong Hu,He Chen,Faustina Pappoe,Qingli Luo,Huiqin Wen,Tian Xing,Yuanhong Xu,Jilong Shen +10 more
TL;DR: Sequencing of the two strains revealed that genome structure of Chinese 1 and type I strains has considerable genomic variations, which may be associated with phenotype and pathogenic differences.
Journal ArticleDOI
Fatal Toxoplasma gondii infection in the giant panda
TL;DR: An acute fatal T. gondii infection in the endangered giant panda in a zoo in China, characterized by acute gastroenteritis and respiratory symptoms, is reported, the first report of clinical toxoplasmosis in a giant p Panda.
Journal ArticleDOI
Molecular detection and genotypic characterization of Toxoplasma gondii infection in bats in four provinces of China
Si-Yuan Qin,Wei Cong,Ye Liu,Nan Li,Zedong Wang,Fu-Kai Zhang,Si-Yang Huang,Xing-Quan Zhu,Quan Liu +8 more
TL;DR: The present study revealed an overall T. gondii prevalence of 6.1% in bats from Jilin, Liaoning, Jiangxi and Guangdong provinces in China, and reported two T. Gondii genotypes (ToxoDB#9 and #10) having a wide geographical distribution in China.
References
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Journal ArticleDOI
Toxoplasma gondii Comprises Three Clonal Lineages: Correlation of Parasite Genotype with Human Disease
D K Howe,L D Sibley +1 more
TL;DR: The population genetic structure of Toxoplasma gondii was determined by multilocus restriction fragment length polymorphism analysis at 6 loci in 106 independent isolates from humans and animals, indicating a highly unusual population structure consisting of 3 widespread clonal lineages.
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Biology and epidemiology of Toxoplasma gondii in man and animals
TL;DR: Toxoplasma gondii is a coccidian parasite which utilizes felids as definitive hosts, and which has an unusually wide intermediate host range, and is one of the most common parasitic infections of man and other warm-blooded animals.
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Moving towards an integrated approach to molecular detection and identification of Toxoplasma gondii.
TL;DR: This review discusses some widely used molecular methods and proposes an integrated approach for the detection and identification of T. gondii, in order to generate maximum information for epidemiological, population and phylogenetic studies of this key pathogen.
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Globalization and the population structure of Toxoplasma gondii
TL;DR: The evidence suggests that South American and Eurasian populations have evolved separately until recently, when ships populated by rats, mice, and cats provided T. gondii with unprecedented migration opportunities, probably during the transatlantic slave trade.
Journal ArticleDOI
Severe Acquired Toxoplasmosis in Immunocompetent Adult Patients in French Guiana
Bernard Carme,F. Bissuel,Daniel Ajzenberg,R. Bouyne,Christine Aznar,Magalie Demar,S. Bichat,D. Louvel,A. M. Bourbigot,C. Peneau,P. Neron,Marie Laure Dardé +11 more
TL;DR: The most common presentation of symptomatic postnatally acquired toxoplasmosis in immunocompetent patients is painless cervical adenopathy, and acute visceral manifestations are associated in rare cases.