Showing papers in "Infection, Genetics and Evolution in 2017"

TL;DR: This study extends the understanding of the genetic diversity of rotaviruses in bats by classified the representative strain into a tentative tenth rotavirus species, provisionally called Rotavirus J.

TL;DR: The designed vaccine is designed to induce cellular, humoral, and innate immune responses against S. aureus, and it is expected that the designed vaccine could defeat antibiotic-resistant staphylococcal infections.

TL;DR: In conclusion, immunoinformatics analysis indicated that this multi-epitope peptide vaccine can be effectively expressed and potentially be used for prophylactic or therapeutic usages against brucellosis.

TL;DR: The results showed that CTB-multiHp could be a good vaccine candidate against H. pylori and the serology analyses indicated that the CT B- multiHp protein produced exhibit immune-reactivity.

TL;DR: The results of in vitro and in vivo experiments, and clinical observations are reviewed to highlight relevant biological and genetic differences between Assemblages, with a focus on human infection.

TL;DR: This review is particularly focused on the common and unique characteristics of Anaplasma marginale and Ana Plasma phagocytophilum, with an emphasis on genetic diversity and evolution, and the main distinguishing features of the diseases caused by the different Ana plasma spp.

TL;DR: The genomic revolution enabled by high-throughput shotgun sequencing should now be considered in order to revise the conservative approaches still informing taxonomic sciences, as genomic data revealed to be much more informative in comparison with phenotype.

TL;DR: A strict co-divergence scenario fails to explain family-wide patterns of diversity, suggesting an important contribution of lineage duplication and, possibly to a lesser extent, recombination and cross-species transmission.

TL;DR: Evaluating the phylogenetic relations and taxonomy of genotypes G1-G3 using sequences of nearly complete mitogenomes and three nuclear loci concludes that these genotypes form a single species E. granulosus s.

TL;DR: Arguments supporting separation of 886-84-like strains into an individual TBEV subtype, which is proposed to name Baikalian (TBEV-Bkl), are presented.

TL;DR: Although there are some indications of a genetic population structure in Southeast Asian countries different from the rest of Asia, more studies in this tropical part of Asia will be necessary for a region which represent as well as Africa one of the missing links of the T. gondii genetic diversity.

TL;DR: Although GM approaches have developed quite rapidly, some caution must be taken during data processing for a reliable biometrical approach, such as allometry and asymmetry analyses, scale removal and wing clarification staining for landmark digitization.

TL;DR: Two comprehensive phylogenetic trees for 78 genome-sequenced Enterobacteriaceae species are constructed based on 2487 core genome proteins, and another set of 118 conserved proteins are analyzed for genetic relatedness based on average amino acid identity and 16S rRNA sequence similarity.

TL;DR: The existence of a novel BTV serotype circulating in goats in Sardinia is proposed, and a specific RT-qPCR targeting Seg 2 of BTV-X ITL2015 was assessed in this study.

TL;DR: This review summarizes the molecular epidemiology, evolution, and phylogeny of C. difficile, one of the most important pathogens worldwide in the current antibiotic resistance era.

TL;DR: It is recommended to considerer companion animals as sentinel surveillance system for zoonotic giardiasis and cryptosporidiosis in order to minimize the risk of spreading of these parasitic diseases among the human population.

TL;DR: It is suggested that the ratio of the number of mite per brood cell in the colony determines the genetic structure of the populations of V. destructor, and this intracolonial population dynamics has great relevance for the selection of acaricide resistance in V.destructor.

TL;DR: The findings reveal that TJnh1501 is a recombinant type 2 PRRSV from the recombinant event between NADC30-like and MLV-like derived from the Chinese highly pathogenic PR RSV, and it exhibits intermediate virulence for pigs.

TL;DR: Three new bat genera and species were newly identified as host of coronaviruses, namely Macroglossus sp.

TL;DR: The results suggest that the p fhrp2 and pfhrp3 deletion phenomenon is present in a considerable proportion in the study areas, thus making the HRP2/3 based rapid diagnostic tests not completely reliable for malaria diagnosis in Eritrea.

TL;DR: The permissiveness of primary human astrocytes for two clinically relevant, Asian and African ZIKV strains are reported and it is shown that both isolates strongly induce antiviral immune responses in these cells albeit with markedly different kinetics.

TL;DR: It is concluded that, although the general trend in the field of complex traits is to shift from GWAS to next-generation sequencing, important knowledge on infectious disease-related traits can be still gained by GWASs, especially for those conditions that have never been investigated using this approach.

TL;DR: The protection against challenge induced by some antigens has been within the lower range described for the ionophores against susceptible isolates or current live vaccines prior to oocyst recycling, and it may be that combinations of anticoccidialAntigens already described are sufficient for development as novel multi-valent vaccines, pending identification of optimal delivery systems.

TL;DR: It is shown that extant strains of the pathogen likely evolved from a South American ancestor, around 1.5 million years ago, and that a new strain has emerged to outcompete the ancestral lineage and undergo a pandemic radiation.

TL;DR: A potential vaccine candidate with proper immunological and physicochemical properties was designed for HPV prophylaxis and is expected to be capable of generating humoral and cellular responses, which are vital for protection against HPV.

TL;DR: It is plausible to assume that exosomes influence the pathogenesis of HIV infection through their biological cargo (primarily membrane proteins and microRNAs), but evidence for a usurpation of the exosomal budding and trafficking machinery by HIV during infection is limited, although such a mechanism cannot be ruled out.

TL;DR: The results indicate a greater diversity of T. cruzi DTUs circulating among autochthonous human Chagas disease cases in the southern US, including for the first time DTUs from the TcII-TcV-tcVI group.

TL;DR: PCR-based tools were used to detect and characterise these protistan parasites from 500 children with a history of diarrhoea in Wuhan and environs, Hubei province, China and no significant gender- or age-associated differences in the prevalence of Cryptosporidium and Giardia infections were found.

TL;DR: Significant percentage of virus prevalence shows potential role in breast cancer development, however, this study provides substantial but not conclusive evidence for the involvement of viruses in BC disease development and progressiveness.

TL;DR: The identification of zoonotic species and the identification of C. parvum subtype IIcA5G3q in livestock, which has previously been identified in children in Ghana, suggests potentialZoonotic transmission.