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Journal ArticleDOI

Forced use of hemiplegic upper extremities to reverse the effect of learned nonuse among chronic stroke and head-injured patients.

TLDR
The data suggest that learned nonuse does occur in select neurological patients and that this behavior can be reversed through application of a forced use paradigm.
About
This article is published in Experimental Neurology.The article was published on 1989-05-01. It has received 917 citations till now. The article focuses on the topics: Constraint-induced movement therapy & Repeated measures design.

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Citations
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Journal ArticleDOI

Principles of Experience-Dependent Neural Plasticity: Implications for Rehabilitation After Brain Damage

TL;DR: 10 principles of experience-dependent neural plasticity and considerations in applying them to the damaged brain are reviewed from the perspective of basic neuroscientists but in a manner intended to be useful for the development of more effective clinical rehabilitation interventions.
Journal ArticleDOI

Effect of constraint-induced movement therapy on upper extremity function 3 to 9 months after stroke: the EXCITE randomized clinical trial.

TL;DR: The Extremity Constraint Induced Therapy Evaluation (EXCITE) trial as mentioned in this paper showed that a 2-week program of constraint-induced movement therapy (CIMT) for patients more than 1 year after stroke who maintain some hand and wrist movement can improve upper extremity function that persists for at least 1 year.
Journal Article

Technique to improve chronic motor deficit after stroke

TL;DR: Extensive restraint of an unaffected upper extremity and practice of functional movements with the impaired limb proved to be an effective means of restoring substantial motor function in stroke patients with chronic motor impairment identified by the inclusion criteria of this project.

Effect of Constraint-Induced Movement Therapy on Upper Extremity Function 3 to 9 Months After Stroke

TL;DR: The Extremity Constraint Induced Therapy Evaluation (EXCITE) trial as discussed by the authors was designed to compare the effects of a 2-week multisite program of CIMT vs usual andcustomary care.
Journal ArticleDOI

Treatment-Induced Cortical Reorganization After Stroke in Humans

TL;DR: This is the first demonstration in humans of a long-term alteration in brain function associated with a therapy-induced improvement in the rehabilitation of movement after neurological injury.
References
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Journal ArticleDOI

Failure to Escape Traumatic Shock

TL;DR: Dogs which had first learned to panel press in a harness in order to escape shock subsequently showed normal acquisition of escape/ avoidance behavior in a shuttle box, supporting a learned "helplessness" explanation of interference with escape responding.
Journal ArticleDOI

Effect of Forced Use of the Upper Extremity of a Hemiplegic Patient on Changes in Function A Single-Case Design

TL;DR: The efficiency and quality of movement scores did not reflect changes related to the period of restraint; however, the frequency of purposeful behaviors and the patient's functional use of her affected extremity increased during the experimental phase.
Journal ArticleDOI

On cerebral motor control: The recovery from experimentally produced hemiplegia.

TL;DR: It has long been believed that if improvement in motor ability does not occur in man within a period of two years following the cerebral accident the paralysis is permanent, but the series of cases show that this is not true, because even in cases of paralysis of eight or more years' duration, considerable improvement follows suitable remedial measures of the nature of exercise.
Journal Article

Central nervous system lesions: sprouting and unmasking in rehabilitation.

TL;DR: Considerable experimental evidence supports the conclusion that the plasticity of the brain is of importance to the functional recovery, and two mechanisms of neuroplasticity considered particularly likely to play a role.
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