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Constraint-Induced Movement Therapy: a new family of techniques with broad application to physical rehabilitation--a clinical review.

TLDR
The CI Therapy approach has been used successfully to date for the upper limb of patients with Chronic and subacute CVA and patients with chronic traumatic brain injury and for the lower limb of Patients with CVA, incomplete spinal cord injury, and fractured hip and has recently been extended to focal hand dystonia of musicians and possibly phantom limb pain.
Abstract
A new family of rehabilitation techniques, termed Constraint-Induced Movement Therapy or CI Therapy, has been developed that controlled experiments have shown is effective in producing large improvements in limb use in the real-world environment after cerebrovascular accident (CVA). The signature therapy involves constraining movements of the less-affected arm with a sling for 90% of waking hours for 2 weeks, while intensively training use of the more-affected arm. The common therapeutic factor in all CI Therapy techniques would appear to be inducing concentrated, repetitive practice of use of the more-affected limb. A number of neuroimaging and transcranial magnetic stimulation studies have shown that the massed practice of CI Therapy produces a massive use-dependent cortical reorganization that increases the area of cortex involved in the innervation of movement of the more-affected limb. The CI Therapy approach has been used successfully to date for the upper limb of patients with chronic and subacute CVA and patients with chronic traumatic brain injury and for the lower limb of patients with CVA, incomplete spinal cord injury, and fractured hip. The approach has recently been extended to focal hand dystonia of musicians and possibly phantom limb pain.

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Treatment-Induced Cortical Reorganization After Stroke in Humans

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Robot-assisted movement training compared with conventional therapy techniques for the rehabilitation of upper-limb motor function after stroke.

TL;DR: Compared with conventional treatment, robot-assisted movements had advantages in terms of clinical and biomechanical measures and was justified into the use of robotic manipulation for motor rehabilitation.
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Virtual reality-enhanced stroke rehabilitation

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References
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Journal ArticleDOI

Increased Cortical Representation of the Fingers of the Left Hand in String Players

TL;DR: The results suggest that the representation of different parts of the body in the primary somatosensory cortex of humans depends on use and changes to conform to the current needs and experiences of the individual.
Journal ArticleDOI

Neural Substrates for the Effects of Rehabilitative Training on Motor Recovery After Ischemic Infarct

TL;DR: The results suggest that, after local damage to the motor cortex, rehabilitative training can shape subsequent reorganization in the adjacent intact cortex, and that the undamaged motor cortex may play an important role in motor recovery.
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