Journal ArticleDOI
From early to late adulthood: Changes in EEG sleep of depressed patients and healthy volunteers
TLDR
REM density appears to be a more likely candidate for a biologic marker for major depression than is REM latency, which was clearly affected by age, but there were no significant differences between patients and controls until the middle of the fourth decade of life.About:
This article is published in Biological Psychiatry.The article was published on 1991-05-15. It has received 233 citations till now. The article focuses on the topics: Non-rapid eye movement sleep & Slow-wave sleep.read more
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Journal ArticleDOI
Meta-Analysis of Quantitative Sleep Parameters From Childhood to Old Age in Healthy Individuals: Developing Normative Sleep Values Across the Human Lifespan
TL;DR: In adults, it appeared that sleep latency, percentages of stage 1 and stage 2 significantly increased with age while percentage of REM sleep decreased, and effect sizes for the different sleep parameters were greatly modified by the quality of subject screening, diminishing or even masking age associations with differentSleep parameters.
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Sleep and depression--results from psychobiological studies: an overview.
TL;DR: Data indicate a strong bi-directional relationship between sleep, sleep alterations and depression, and most of the effective antidepressant agents suppress REM sleep.
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Sleep and mental disorders: A meta-analysis of polysomnographic research.
Chiara Baglioni,Svetoslava Nanovska,Wolfram Regen,Kai Spiegelhalder,Bernd Feige,Christoph Nissen,Charles F. Reynolds,Dieter Riemann +7 more
TL;DR: A meta-analysis aimed at determining the polysomnographic characteristics of several mental disorders found sleep depth and REM pressure alterations were associated with affective, anxiety, autism and schizophrenia disorders, and comorbidity was associated with enhanced REM sleep pressure.
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Polysomnographically measured sleep abnormalities in PTSD: A meta-analytic review.
TL;DR: A meta-analytic review of polysomnographic studies comparing sleep in people with and without PTSD suggested that sleep abnormalities exist in PTSD, and that some of the inconsistencies in prior findings may be explained by moderating variables.
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REM sleep dysregulation in depression: State of the art
TL;DR: It is hypothesize on the one hand that REM sleep dysregulation in depression may be linked to a genetic predisposition/vulnerability to develop the illness; on the other hand it is conceivable thatREM sleep disinhibition in itself is a part of a maladaptive stress reaction with increased allostatic load.
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