Journal ArticleDOI
Polysomnographically measured sleep abnormalities in PTSD: A meta-analytic review.
TLDR
A meta-analytic review of polysomnographic studies comparing sleep in people with and without PTSD suggested that sleep abnormalities exist in PTSD, and that some of the inconsistencies in prior findings may be explained by moderating variables.Abstract:
Although sleep complaints are common among patients with Posttraumatic stress disorder (PTSD), polysomnographic studies examining sleep abnormalities in PTSD have produced inconsistent results. To clarify discrepant findings, we conducted a meta-analytic review of 20 polysomnographic studies comparing sleep in people with and without PTSD. Results showed that PTSD patients had more stage 1 sleep, less slow wave sleep, and greater rapid-eye-movement density compared to people without PTSD. We also conducted exploratory analyses aimed at examining potential moderating variables (age, sex, and comorbid depression and substance use disorders). Overall, studies with a greater proportion of male participants or a low rate of comorbid depression tended to find more PTSD-related sleep disturbances. These findings suggest that sleep abnormalities exist in PTSD, and that some of the inconsistencies in prior findings may be explained by moderating variables.read more
Citations
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Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: a web-based cross-sectional survey.
Yeen Huang,Ning Zhao,Ning Zhao +2 more
TL;DR: This study identified a major mental health burden of the public during the COVID-19 outbreak as young people, people spending too much time thinking about the outbreak, and healthcare workers were at high risk of mental illness.
Journal ArticleDOI
Biological studies of post-traumatic stress disorder
Roger K. Pitman,Ann M. Rasmusson,Ann M. Rasmusson,Karestan C. Koenen,Lisa M. Shin,Lisa M. Shin,Scott P. Orr,Mark W. Gilbertson,Mark W. Gilbertson,Mark W. Gilbertson,Mohammed R. Milad,Israel Liberzon,Israel Liberzon +12 more
TL;DR: This Review attempts to present the current state of understanding of post-traumatic stress disorder on the basis of psychophysiological, structural and functional neuroimaging, and endocrinological, genetic and molecular biological studies in humans and in animal models.
Journal ArticleDOI
Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease
TL;DR: It is proposed that brain disorders and abnormal sleep have a common mechanistic origin and that many co-morbid pathologies that are found in brain disease arise from a destabilization of sleep mechanisms.
Journal ArticleDOI
Disturbed sleep in post-traumatic stress disorder: secondary symptom or core feature?
TL;DR: A growing body of evidence shows that disturbed sleep is more than a secondary symptom of PTSD-it seems to be a core feature, and sleep-focused treatment can be incorporated into any standard PTSD treatment, and PTSD research needs to start including validated sleep measurements in longitudinal epidemiologic and treatment outcome studies.
Journal ArticleDOI
Sleep Disturbances as the Hallmark of PTSD: Where Are We Now?
TL;DR: Overall, the literature suggests that disturbed REM or non-REM sleep can contribute to maladaptive stress and trauma responses and may constitute a modifiable risk factor for poor psychiatric outcomes.
References
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Journal ArticleDOI
A power primer.
TL;DR: A convenient, although not comprehensive, presentation of required sample sizes is providedHere the sample sizes necessary for .80 power to detect effects at these levels are tabled for eight standard statistical tests.
Journal ArticleDOI
Posttraumatic stress disorder in the National Comorbidity Survey.
TL;DR: Progress in estimating age-at-onset distributions, cohort effects, and the conditional probabilities of PTSD from different types of trauma will require future epidemiologic studies to assess PTSD for all lifetime traumas rather than for only a small number of retrospectively reported "most serious" traumAs.
Journal ArticleDOI
Meta-Analysis of Quantitative Sleep Parameters From Childhood to Old Age in Healthy Individuals: Developing Normative Sleep Values Across the Human Lifespan
TL;DR: In adults, it appeared that sleep latency, percentages of stage 1 and stage 2 significantly increased with age while percentage of REM sleep decreased, and effect sizes for the different sleep parameters were greatly modified by the quality of subject screening, diminishing or even masking age associations with differentSleep parameters.
Journal ArticleDOI
Sex differences in trauma and posttraumatic stress disorder: a quantitative review of 25 years of research.
David F. Tolin,Edna B. Foa +1 more
TL;DR: Meta-analyses of studies yielding sex-specific risk of potentially traumatic events (PTEs) and posttraumatic stress disorder (PTSD) indicated that female participants were more likely than male participants to meet criteria for PTSD, although they were less likely to experience PTEs.
Journal ArticleDOI
Sleep disturbance and psychiatric disorders: A longitudinal epidemiological study of young Adults
TL;DR: Prior insomnia remained a significant predictor of subsequent major depression when history of other prior depressive symptoms was controlled for, and complaints of 2 weeks or more of insomnia nearly every night might be a useful marker of subsequent onset of major depression.