Journal ArticleDOI
Functional neuroimaging of acute oculomotor deficits in concussed athletes
Brian F. G. Johnson,Kai Zhang,Mark Hallett,Semyon Slobounov,Semyon Slobounov,Semyon Slobounov +5 more
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TLDR
As a potential diagnostic and management tool for concussion, oculomotor testing shows promise, and here it is tried to understand the reasons for this disrupted performance with the aide of advanced neuroimaging tools.Abstract:
In the pursuit to better understand the neural underpinnings of oculomotor deficits following concussion we performed a battery of oculomotor tests while performing simultaneous functional magnetic resonance imaging (fMRI). Based on the increasing evidence that concussion can disrupt multiple brain functional networks, including the oculomotor control networks, a series of classic saccadic and smooth pursuit tasks were implemented. Nine concussed athletes were tested within seven days of injury along with nine age and sex matched healthy normal volunteers. Both behavioral and fMRI data revealed differential results between the concussed and normal volunteer groups. Concussed subjects displayed longer latency time in the saccadic tasks, worse position errors, and fewer numbers of self-paced saccades compared to normal volunteer subjects. Furthermore, the concussed group showed recruitment of additional brain regions and larger activation sites as evidenced by fMRI. As a potential diagnostic and management tool for concussion, oculomotor testing shows promise, and here we try to understand the reasons for this disrupted performance with the aide of advanced neuroimaging tools.read more
Citations
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Journal ArticleDOI
Role of advanced neuroimaging, fluid biomarkers and genetic testing in the assessment of sport-related concussion: a systematic review.
Michael McCrea,Timothy B. Meier,Daniel L. Huber,Alain Ptito,Erin D. Bigler,Chantel T. Debert,Geoff Manley,David K. Menon,Jen-Kai Chen,Rachel Wall,Kathryn J Schneider,Thomas W. McAllister +11 more
TL;DR: A systematic review of published literature on advanced neuroimaging, fluid biomarkers and genetic testing in the assessment of sport-related concussion (SRC) was conducted in this article, where the authors used a modified quality assessment of studies of diagnostic accuracy studies (QUADAS-2) tool to rate the risk of bias, and a modified Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system to rank the overall level of evidence for each search.
Role of advanced neuroimaging, fluid biomarkers and genetic testing in the assessment of sport-related concussion: a systematic review
Michael McCrea,Timothy B. Meier,Daniel L. Huber,Alain Ptito,Erin D. Bigler,Chantel T. Debert,Geoff Manley,David K. Menon,Jen-Kai Chen,Rachel Wall,Kathryn J Schneider,Thomas W. McAllister +11 more
TL;DR: Advanced neuroimaging, fluid biomarkers and genetic testing are important research tools, but require further validation to determine their ultimate clinical utility in the evaluation of sport-related concussion (SRC).
Journal ArticleDOI
Ocular motor assessment in concussion: Current status and future directions
TL;DR: A combination of eye movement tasks coupled with neuroimaging techniques and other objective biomarkers may lead to a better understanding of the anatomical and physiological consequences of concussion and to better understand the natural history of this condition.
Journal ArticleDOI
Association of Football Subconcussive Head Impacts With Ocular Near Point of Convergence.
Keisuke Kawata,Leah H. Rubin,Jong Hyun Lee,Thomas Sim,Masahiro Takahagi,Victor Szwanki,Al Bellamy,Kurosh Darvish,Soroush Assari,Jeffrey D Henderer,Ryan Tierney,Dianne Langford +11 more
TL;DR: It is suggested that repetitive subconcussive head impacts during preseason football practice cause changes in near point of convergence (NPC) ocular-motor function and changes in NPC may become a useful clinical tool in deciphering brain injury severity.
Journal ArticleDOI
Visual problems associated with traumatic brain injury
TL;DR: Patients with chronic dysfunction following TBI may require occupational, vestibular, cognitive and other forms of physical therapy and benefit from visual rehabilitation, including reading‐related oculomotor training and the prescribing of spectacles with a variety of tints and prism combinations.
References
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Journal ArticleDOI
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TL;DR: An overview of the epidemiology and impact of TBI is presented, which shows that the number of Americans living with TBI-related disability and their efforts to return to a full and productive life are increasing.
Journal ArticleDOI
Functional Magnetic Resonance Imaging
TL;DR: FMRI reveals short-term physiological changes associated with active brain functioning, and in this way, fMRI can identify different parts of the brain where particular men-tal processes occur and can characterize the patterns of acti-vation associated with those processes.
Journal ArticleDOI
Consensus statement on concussion in sport--the 4th International Conference on Concussion in Sport held in Zurich, November 2012.
Paul McCrory,Willem H. Meeuwisse,Karen M. Johnston,Jiri Dvorak,Mark Aubry,Mick Molloy,Robert C. Cantu +6 more
TL;DR: The 4th International Conference on Concussion in Sport held in Zurich, November 2012 was attended by Paul McCrory, Willem H Meeuwisse, Mark Aubry, Jiří Dvořák, Ruben J Echemendia, Lars Engebretsen, Karen Johnston, Jeffrey S Kutcher, Martin Raftery, Allen Sills and Kathryn Schneider.
Journal ArticleDOI
National Athletic Trainers' Association Position Statement: Management of Sport Concussion
Steven P. Broglio,Robert C. Cantu,Gerard A. Gioia,Kevin M. Guskiewicz,Jeffrey S. Kutcher,Michael Palm,Tamara C. Valovich McLeod +6 more
TL;DR: The recommendations for concussion management provided here are based on the most current research and divided into sections on education and prevention, documentation and legal aspects, evaluation and return to play, and other considerations.
Journal ArticleDOI
Consensus statement on concussion in sport: the 3rd International Conference on Concussion in Sport held in Zurich, November 2008
Paul McCrory,Willem H. Meeuwisse,Karen M. Johnston,Jiri Dvorak,Mark Aubry,Michael G. Molloy,Robert C. Cantu +6 more
TL;DR: This paper is a revision and update of the recommendations developed following the 1st (Vienna) and 2nd (Prague) International Symposia on Concussion in Sport and is designed to build on the principles outlined in the original Vienna and Prague documents.
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