Gastric Cancer: Descriptive Epidemiology, Risk Factors, Screening, and Prevention
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TLDR
The epidemiology, screening, and prevention of gastric cancer are reviewed, including its incidence, survival, mortality, and trends over time, and risk factors are characterized, both environmental and genetic.Abstract:
Less than a century ago, gastric cancer (GC) was the most common cancer in the United States and perhaps throughout the world. Despite its worldwide decline in incidence over the past century, GC remains a major killer across the globe. This article reviews the epidemiology, screening, and prevention of gastric cancer. We first discuss the descriptive epidemiology of GC, including its incidence, survival, and mortality, including trends over time. Next, we characterize the risk factors for gastric cancer, both environmental and genetic. Serological markers and histological precursor lesions of GC and early detection of GC of using these markers is reviewed. Finally, we discuss prevention strategies and provide suggestions for further research.read more
Citations
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Global Cancer Incidence and Mortality Rates and Trends—An Update
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Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States
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Cancer statistics for African Americans, 2016: Progress and opportunities in reducing racial disparities
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