Cancer statistics in China, 2015
Wanqing Chen,Rongshou Zheng,Peter D. Baade,Siwei Zhang,Hongmei Zeng,Freddie Bray,Ahmedin Jemal,Xue Qin Yu,Jie He +8 more
TLDR
Many of the estimated cancer cases and deaths can be prevented through reducing the prevalence of risk factors, while increasing the effectiveness of clinical care delivery, particularly for those living in rural areas and in disadvantaged populations.Abstract:
With increasing incidence and mortality, cancer is the leading cause of death in China and is a major public health problem. Because of China's massive population (1.37 billion), previous national incidence and mortality estimates have been limited to small samples of the population using data from the 1990s or based on a specific year. With high-quality data from an additional number of population-based registries now available through the National Central Cancer Registry of China, the authors analyzed data from 72 local, population-based cancer registries (2009-2011), representing 6.5% of the population, to estimate the number of new cases and cancer deaths for 2015. Data from 22 registries were used for trend analyses (2000-2011). The results indicated that an estimated 4292,000 new cancer cases and 2814,000 cancer deaths would occur in China in 2015, with lung cancer being the most common incident cancer and the leading cause of cancer death. Stomach, esophageal, and liver cancers were also commonly diagnosed and were identified as leading causes of cancer death. Residents of rural areas had significantly higher age-standardized (Segi population) incidence and mortality rates for all cancers combined than urban residents (213.6 per 100,000 vs 191.5 per 100,000 for incidence; 149.0 per 100,000 vs 109.5 per 100,000 for mortality, respectively). For all cancers combined, the incidence rates were stable during 2000 through 2011 for males (+0.2% per year; P = .1), whereas they increased significantly (+2.2% per year; P < .05) among females. In contrast, the mortality rates since 2006 have decreased significantly for both males (-1.4% per year; P < .05) and females (-1.1% per year; P < .05). Many of the estimated cancer cases and deaths can be prevented through reducing the prevalence of risk factors, while increasing the effectiveness of clinical care delivery, particularly for those living in rural areas and in disadvantaged populations.read more
Citations
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Patients with Cancer Appear More Vulnerable to SARS-CoV-2: A Multicenter Study during the COVID-19 Outbreak.
Meng-Yuan Dai,Dianbo Liu,Dianbo Liu,Miao Liu,Fuxiang Zhou,Gui-Ling Li,Zhen Chen,Zhi-An Zhang,Hua You,Meng Wu,Qi-Chao Zheng,Yong Xiong,Hui-Hua Xiong,Chun Wang,Chang-Chun Chen,Fei Xiong,Yan Zhang,Ya-Qin Peng,Si-Ping Ge,Bo Zhen,Ting-Ting Yu,Ling Wang,Hua Wang,Yu Liu,Ye-Shan Chen,Jun-Hua Mei,Xiao-Jia Gao,Zhu-Yan Li,Li-Juan Gan,Can He,Zhen Li,Yu-Ying Shi,Yu-Wen Qi,Jing Yang,Daniel G. Tenen,Daniel G. Tenen,Li Chai,Lorelei A. Mucci,Mauricio Santillana,Mauricio Santillana,Hongbing Cai +40 more
TL;DR: In a study of 105 patients with cancer and 536 without, all with confirmed COVID-19, cancer was predictive of more severe disease, with stage IV cancer, hematologic cancer, and lung cancer being associated with worse outcomes.
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Current cancer situation in China: Good or bad news from the 2018 Global Cancer Statistics?
TL;DR: China is undergoing the cancer transition stage where the cancer spectrum is changing from developing country to developed country, with a rapidly increase cancer burden of colorectal, prostate, female breast cancers in addition to a high occurrence of infection-related and digestive cancers.
Journal ArticleDOI
Changing profiles of cancer burden worldwide and in China: a secondary analysis of the global cancer statistics 2020.
TL;DR: China is undergoing cancer transition with an increasing burden of lung cancer, gastrointestinal cancer, and breast cancers, and the burden of breast cancer is increasing globally.
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Epidemiology of ovarian cancer: a review.
TL;DR: The epidemiology provides clues on etiology, primary prevention, early detection, and possibly even therapeutic strategies for OC, including parity, oral contraceptive use, and lactation.
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Role of hypoxia in cancer therapy by regulating the tumor microenvironment
TL;DR: The role of Hypoxia in cancer therapy by regulating the tumor microenvironment (TME) is summarized and the potential of hypoxia-targeted therapy is highlighted to overcome hypoxian-associated resistance in cancer treatment.
References
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Book
Cancer Incidence in Five Continents
Freddie Bray,J. Ferlay,Mathieu Laversanne,David H. Brewster,C. Gombe Mbalawa,B. Kohler,Marion Piñeros,Eva Steliarova-Foucher,Rajaraman Swaminathan,Sebastien Antoni,Isabelle Soerjomataram,David Forman +11 more
TL;DR: The aim of this study was to establish a database of histological groups and to provide a level of consistency and quality of data that could be applied in the design of future registries.