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Gender differences in the disposition and toxicity of metals

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TLDR
Gender differences in susceptibility at lower exposure are uncertain, but recent data indicate that cadmium has estrogenic effects and affect female offspring, and experimental data suggest that females are more susceptible to immunotoxic effects of lead.
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This article is published in Environmental Research.The article was published on 2007-05-01. It has received 599 citations till now.

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Current status of cadmium as an environmental health problem.

TL;DR: It can be anticipated that a considerable proportion of the non-smoking adult population has urinary cadmium concentrations of 0.5 microg/g creatinine or higher in non-exposed areas, and for smokers this proportion is considerably higher, which implies no margin of safety between the point of departure and the exposure levels in the general population.
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Plant science: the key to preventing slow cadmium poisoning

TL;DR: Recent studies on rice (Oryza sativa) and Cd-hyperaccumulating plants that have led to important insights into the processes controlling the passage of Cd from the soil to edible plant organs are reviewed.
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Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic.

TL;DR: In this paper, the authors reviewed the mechanistic action of heavy metals according to the available animal and human studies and found similar pathways for these metals to induce toxicity including ROS generation, weakening of the antioxidant defense, enzyme inactivation, and oxidative stress.
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Cadmium and Its Neurotoxic Effects

TL;DR: The available finding indicates the neurotoxic effects of Cd that was associated with both biochemical changes of the cell and functional changes of central nervous system, suggesting that neurot toxic effects may play a role in the systemic toxic effects of the exposure to Cd, particularly the long-term exposure.
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Environmental toxicants and autism spectrum disorders: a systematic review

TL;DR: The findings of this review suggest that the etiology of ASD may involve, at least in a subset of children, complex interactions between genetic factors and certain environmental toxicants that may act synergistically or in parallel during critical periods of neurodevelopment, in a manner that increases the likelihood of developing ASD.
References
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Journal ArticleDOI

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

TL;DR: A new metal-ion transporter in the rat, DCT1, which has an unusually broad substrate range that includes Fe2+, Zn2+, Mn2+, Co2+, Cd2+, Cu2+, Ni2+ and Pb2+.

Arsenic in Drinking Water

TL;DR: Arsenic in drinking water: not just a problem for Bangladesh D. van Halem, S. A. Bakker, G. L. Amy, and J. C. van Dijk Delft University of Technology.
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Health effects of cadmium exposure - a review of the literature and a risk estimate

TL;DR: A review article is published on environmental risk factors in breast cancer by Esther A Welp and her co-workers and concludes with several proposals for future studies.
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Lead neurotoxicity in children: basic mechanisms and clinical correlates.

Theodore I. Lidsky, +1 more
- 01 Jan 2003 - 
TL;DR: The present review discusses the current state of knowledge concerning the effects of lead on the cognitive development of children, and suggests that there are toxicological effects with behavioural concomitants at exceedingly low levels of exposure.
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Effects and dose-response relationships of skin cancer and blackfoot disease with arsenic

TL;DR: The degree of permanent impairment of function in the patient was directly related to duration of intake of arsenical water and toduration of such intake at the time of onset, i.e., the higher the arsenic content of well water, the more patients with skin cancer and blackfoot disease.
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