Journal ArticleDOI
Gonadal dysfunction in uremic men. A study of the hypothalamo-pituitary-testicular axis before and after renal transplantation.
Victoria S. Lim,Victor S. Fang +1 more
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It is postulated that a defect in that portion of the hypothalamus involved in the receipt and/or interpretation of message might be at fault in uremia.About:
This article is published in The American Journal of Medicine.The article was published on 1975-05-01. It has received 194 citations till now. The article focuses on the topics: Luteinizing hormone & Transplantation.read more
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Thyroid Dysfunction in Chronic Renal Failure: A STUDY OF THE PITUITARY-THYROID AXIS AND PERIPHERAL TURNOVER KINETICS OF THYROXINE AND TRIIODOTHYRONINE
TL;DR: It appears that uremia affects thyroid function at several levels: (a) subnormal pituitary TSH response to TRH; (b) possible intrathyroidal abnormalities as suggested by slightly decreased TT(4) and high incidence of goiter; and (c) abnormal peripheral generation of T(3) from T(4).
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The Pituitary-Testicular Axis in Men with Chronic Renal Failure
TL;DR: Chronic renal failure interferes with testicular steroid production and spermatogenesis, and the effects of uremia on the pituitary-testicular axis in 35 men with creatinine clearances less than 4 ml per minute per 1.7m was studied.
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Ovarian Function in Chronic Renal Failure: Evidence Suggesting Hypothalamic Anovulation
TL;DR: In uremic women, the continued secretion of estrogen, the rise of plasma levels of luteinizing hormone, FSH, and estradiol after clomiphene, and the elevated gonadotropin levels during menopause suggest that the negativeEstradiol feedback, the tonic gonadotropic secretion, andThe pituitary ovarian axis were normal.
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Protein Nutrition and Malnutrition in CKD and ESRD.
TL;DR: Thorough understanding the pathogenesis and etiology of protein malnutrition in CKD and ESRD patients will undoubtedly facilitate the design and development of more effective strategies to optimize protein nutrition and improve outcomes.
References
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Simplified, partially automated method for radioimmunoassay of human thyroid-stimulating, growth, luteinizing, and follicle stimulating hormones.
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Radioimmunoassay for Luteinizing Hormone in Human plasma Or Serum: Physiological Studies*
TL;DR: Levels were remarkably constant in men from day to day and in women except at midcycle, when a sharp peak occurred lasting less than 24 hours, and mean plasma LH levels during the follicular phase of the menstrual cycle were higher than mean values obtained during the luteal phase.
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Impotence in Diabetes: The Neurologic Factor
TL;DR: In this chapter, Ellenberg describes a study undertaken to investigate the influence of endocrine, neurologic, and urologic factors in the etiology of impotence in diabetic males.
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Comparison of the regulation of luteinizing hormone (LH) secretion in immature and adult rats.
Domingo V. Ramirez,S. M. McCann +1 more
TL;DR: Two to 3 weeks following gonadectomy, pituitary LH content had risen significantly in both adult females and immature males, whereas it remained unchanged in immature females and adult males, while plasma LH activity increased significantly in all gonadectomized groups.
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Hormonal, Histological and Chromosomal Studies in Adult Males with Testicular Disorders
TL;DR: Data indicate that previous concepts that isolated defects of spermatogenesis exist in all such patients have been erroneous, particularly in the category of Sertoli-cell-only syndrome.