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Journal ArticleDOI

Growth and acid production by Lactobacillus (L.) delbrueckii in a dialysis culture system

Morton R. Friedman, +1 more
- 01 Nov 1970 - 
- Vol. 12, Iss: 6, pp 961-974
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TLDR
It has been shown that lactate inhibits growth after the log phase and that the maintenance of low lactate concentrations after this point permits higher specific growth rates and higher maximum cell concentrations.
Abstract
Growth and lactic acid production by L. delbrueckii was studied in a dialysis culture system and the inhibitory effect of lactate confirmed by removing lactate from the culture medium by dialysis. It has been shown that lactate inhibits growth after the log phase and that the maintenance of low lactate concentrations after this point permits higher specific growth rates and higher maximum cell concentrations. Acid production is also significantly higher in a dialysis culture system. Finally, a modification of the Luedeking‐Piret model, incorporating the lactate inhibition effect, is proposed.

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Book ChapterDOI

Chapter 5 - Immobilized Cells

Book ChapterDOI

Fermentation Processes for the Production of Lactic Acid

TL;DR: As with many other biotechnological processes, lactic acid fermentation has evolved from an ancient "art" associated with the processing and preservation of foodstuffs, to a presently sophisticated technology as mentioned in this paper.
Journal ArticleDOI

Lactic acid production by a filter-bed-type reactor

TL;DR: In this article, a novel membrane reactor, named a filter-bed-type reactor, was designed to produce lactic acid, which was equipped with a membrane filter to immobilize cells of Streptococcus faecalis, was operated continuously for two weeks.
Book ChapterDOI

Bioconversion of cheese whey to organic acids

R. D. Tyagi, +1 more
TL;DR: In many countries, including Canada, most of the whey is discarded as waste creating severe pollution problems owing to its biological oxygen demand (BOD) (35 000-40 000 ppm) as discussed by the authors.
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Augmentation of mass transfer through electrical means for hydrogel‐entrapped Escherichia coli cultivation

TL;DR: A mathematical model taking into account nutrient depletion, inhibitory end‐product formation, and cell growth kinetics under facultatively anaerobic conditions was developed to rationalize the overall transport and biological behaviors in the hydrogel.
References
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Journal ArticleDOI

Limiting factors in the lactic fermentation

TL;DR: A microscopic count was used in order to avoid as far as possible the error introduced into the plate method by the tendency of the lactic streptococci to grow in pairs and chains.
Journal ArticleDOI

Dialysis Fermentor Systems for Concentrated Culture of Microorganisms.

TL;DR: Cell-mass production of Serratia marcescens was studied in dialysis systems in which growth was managed in a fermentor remote from, but connected by conduits and pumps with, a nutrient reservoir, believed to be adaptable to any desired scale of size.
Journal ArticleDOI

Penicillin production in corn steep media with continuous carbohydrate addition.

TL;DR: The work reported here presents the results of an investigation into the replacement of lactose by glucose or by sucrose in a corn steep liquor medium for the production of penicillin.
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