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Journal ArticleDOI

Growth and acid production by Lactobacillus (L.) delbrueckii in a dialysis culture system

Morton R. Friedman, +1 more
- 01 Nov 1970 - 
- Vol. 12, Iss: 6, pp 961-974
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TLDR
It has been shown that lactate inhibits growth after the log phase and that the maintenance of low lactate concentrations after this point permits higher specific growth rates and higher maximum cell concentrations.
Abstract
Growth and lactic acid production by L. delbrueckii was studied in a dialysis culture system and the inhibitory effect of lactate confirmed by removing lactate from the culture medium by dialysis. It has been shown that lactate inhibits growth after the log phase and that the maintenance of low lactate concentrations after this point permits higher specific growth rates and higher maximum cell concentrations. Acid production is also significantly higher in a dialysis culture system. Finally, a modification of the Luedeking‐Piret model, incorporating the lactate inhibition effect, is proposed.

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Mathematical model of microporous hollow‐fiber membrane extractive fermentor

TL;DR: A mathematical model is presented for a microporous hollow‐fiber membrane extractive fermentor which predicts the existence of an optimum volume fraction of hollow fibers in the fermentor that maximizes the total volumetric productivity.
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Chitosan‐treated polypropylene matrix as immobilization support for lactic acid production using Lactobacillus plantarum NCIM 2084

TL;DR: In this article, cells of Lactobacillus plantarum NCIM 2084 were immobilized on a polypropylene (PP) matrix treated with different concentrations of chitosan.
Journal ArticleDOI

Sorption of mono-carboxylic acids by an anion-exchange membrane

TL;DR: In this paper, an ion exchange between a dissociated carboxylic acid ion and a counter ion on the fixed charge in an anion exchange membrane has been studied, and the selectivity coefficients of mono-carboxyl acid were determined by a model which considered with dissociation equilibrium of carboxyl acids, material balance in the solution, and electrical neutrality in the membrane.
Journal ArticleDOI

Mathematic model for lactic acid formation with Streptococcus cremoris from glucose

TL;DR: A model for lactic acid production is suggested which fits the experimental data from the chemostat better than previously proposed models, a modification of the original Luedeking-Piret expression including a term with negative substrate dependence.
Journal ArticleDOI

On‐line estimation of biological variables during pH controlled lactic acid fermentations

TL;DR: The results showed the feasibility of on‐line estimation of biomass concentration and of the specific kinetics from NaOH addition weight measurements and its applicability for monitoring lactic acid fermentations.
References
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Journal ArticleDOI

Limiting factors in the lactic fermentation

TL;DR: A microscopic count was used in order to avoid as far as possible the error introduced into the plate method by the tendency of the lactic streptococci to grow in pairs and chains.
Journal ArticleDOI

Dialysis Fermentor Systems for Concentrated Culture of Microorganisms.

TL;DR: Cell-mass production of Serratia marcescens was studied in dialysis systems in which growth was managed in a fermentor remote from, but connected by conduits and pumps with, a nutrient reservoir, believed to be adaptable to any desired scale of size.
Journal ArticleDOI

Penicillin production in corn steep media with continuous carbohydrate addition.

TL;DR: The work reported here presents the results of an investigation into the replacement of lactose by glucose or by sucrose in a corn steep liquor medium for the production of penicillin.
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