scispace - formally typeset
Journal ArticleDOI

Growth and acid production by Lactobacillus (L.) delbrueckii in a dialysis culture system

Morton R. Friedman, +1 more
- 01 Nov 1970 - 
- Vol. 12, Iss: 6, pp 961-974
Reads0
Chats0
TLDR
It has been shown that lactate inhibits growth after the log phase and that the maintenance of low lactate concentrations after this point permits higher specific growth rates and higher maximum cell concentrations.
Abstract
Growth and lactic acid production by L. delbrueckii was studied in a dialysis culture system and the inhibitory effect of lactate confirmed by removing lactate from the culture medium by dialysis. It has been shown that lactate inhibits growth after the log phase and that the maintenance of low lactate concentrations after this point permits higher specific growth rates and higher maximum cell concentrations. Acid production is also significantly higher in a dialysis culture system. Finally, a modification of the Luedeking‐Piret model, incorporating the lactate inhibition effect, is proposed.

read more

Citations
More filters
Journal ArticleDOI

Batch fermentation of whey ultrafiltrate by Lactobacillus helveticus for lactic acid production

TL;DR: Cheese whey ultrafiltrate (WU) was used as the carbon source for the production of lactic acid by batch fermentation with Lactobacillus helveticus strain milano, which will provide an alternative solution to the phage contamination in dairy industries using LactOBacillus bulgaricus.
Journal ArticleDOI

Extractive lactic acid fermentation using ion-exchange resin.

TL;DR: The effect of temperature on extractive fermentation was remarkable and has been included in this work.
Journal ArticleDOI

In situ recovery of fermentation products

TL;DR: In situ recovery of fermentation products can increase the rate of product inhibited fermentations, reduce costs of waste-water treatment and minimize product degradation as mentioned in this paper, and some methods of in situ recovery show more potential than others for the production of chemicals and pharmaceuticals by fermentation.
Journal ArticleDOI

Lactic acid production by Lactobacillus delbreuckii in a hollow fiber fermenter

TL;DR: Lactic acid was produced by viable Lactobacillus delbreuckii NRRL-B445 in a hollow fiber fermenter and the observed cell yields were appreciably lower than batch cell yields.
References
More filters
Journal ArticleDOI

Limiting factors in the lactic fermentation

TL;DR: A microscopic count was used in order to avoid as far as possible the error introduced into the plate method by the tendency of the lactic streptococci to grow in pairs and chains.
Journal ArticleDOI

Dialysis Fermentor Systems for Concentrated Culture of Microorganisms.

TL;DR: Cell-mass production of Serratia marcescens was studied in dialysis systems in which growth was managed in a fermentor remote from, but connected by conduits and pumps with, a nutrient reservoir, believed to be adaptable to any desired scale of size.
Journal ArticleDOI

Penicillin production in corn steep media with continuous carbohydrate addition.

TL;DR: The work reported here presents the results of an investigation into the replacement of lactose by glucose or by sucrose in a corn steep liquor medium for the production of penicillin.
Related Papers (5)