scispace - formally typeset
Journal ArticleDOI

Hemagglutination Assay for Antigen and Antibody Associated with Viral Hepatitis

Girish N. Vyas, +1 more
- 16 Oct 1970 - 
- Vol. 170, Iss: 3955, pp 332-333
Reads0
Chats0
TLDR
The hemagglutination test has the sensitivity and rapidity of the best tests available, is simpler to perform, and lends itself to large-scale screening of blood donors.
Abstract: 
Hemagglutination assays are described for measuring hepatitis-associated Australia antigen and antibody. Red cells coated with isolated antigen, with chromic chloride as a coupling agent, are used for detection of antibodies. Detection of the antigen in serums depends on inhibition of hemagglutination. The test has the sensitivity and rapidity of the best tests available, is simpler to perform, and lends itself to large-scale screening of blood donors.

read more

Citations
More filters
Journal ArticleDOI

Interrelationship of blood transfusion, non‐A, non‐B hepatitis and hepatocellular carcinoma: Analysis by detection of antibody to hepatitis C virus

Kendo Kiyosawa, +10 more
- 01 Oct 1990 - 
TL;DR: The slow, sequential progression from acute hepatitis C virus—related non‐A, non‐B hepatitis through chronic hepatitis and cirrhosis to hepatocellular carcinoma is suggested to support a causal association between hepatitis Cirus and hepato Cell carcinoma.
Journal ArticleDOI

Vertical transmission of hepatitis B antigen in Taiwan.

C E Stevens, +3 more
- 10 Apr 1975 - 
TL;DR: It is indicated that vertical transmission from carrier mothers frequently occurs, at least in Taiwan, and may partially explain Taiwan's high prevalence of HB5 Ag.
Journal ArticleDOI

Study of an epidemic of non-A, non-B, hepatitis. Possibility of another human hepatitis virus distinct from post-transfusion non-A, non-B type.

Mohammed Sultan Khuroo
- 01 Jun 1980 - 
TL;DR: The data strongly suggest the possibility of another human hepatitis virus and established the fecal oral route of its spread.
Journal ArticleDOI

Transfusion-associated hepatitis not due to viral hepatitis type A or B.

Stephen M. Feinstone, +4 more
- 10 Apr 1975 - 
TL;DR: In this paper, 22 patients who had an episode of transfusion-associated hepatitis not positive for hepatitis B antigen were examined for development of antibody to heaptitis A and B antigens, cytomegalovirus and Epstein-Barr virus.
Journal ArticleDOI

Effect of Human Leukocyte Interferon on Hepatitis B Virus Infection in Patients with Chronic Active Hepatitis

Harry B. Greenberg, +5 more
- 02 Sep 1976 - 
TL;DR: Parenteral interferon therapy was associated with a rapid and reproducible fall in all Dane-particle markers in four patients with chronic hepatitis B infection and chronic active hepatitis and may be useful in limiting carrier infectivity or eradicating chronic infection.
References
More filters
Journal ArticleDOI

An antigen detected in the blood during the incubation period of serum hepatitis

Alfred M. Prince
- 01 Jul 1968 - 
TL;DR: An antigen that reacted in the immunodiffusion test with serum from multiply transfused patients was detected in the blood during the incubation period prior to the onset of major chemical or clinical abnormalities, suggesting this antigen is specific for serum hepatitis virus.
Journal Article

Chromic Chloride: A Coupling Reagent for Passive Hemagglutination Reactions

E R Gold, +1 more
- 01 Nov 1967 - 
TL;DR: The present studies showed that group O human red cells coated with antigen by the CrCl3 procedure can be used in a number of serologic reactions, and use of CrCl 3-treated cells as immunoadsorbent provides a rapid method for the preparation of monospecific antisera to human immunoglobulins.
Journal ArticleDOI

A Simple Hemagglutination System Requiring Small Amounts of Red Cells and Antibodies

Thomas G. Wegmann, +1 more
- 02 Jan 1966 - 
TL;DR: A method is described which permits dilute red cell suspensions to be used in plastic microtiter plates for detecting hemagglutinins at unusually high dilutions, and quantitative studies demonstrate the discriminatory powers of the technic.
Journal ArticleDOI

Virus-like antigen, antibody, and antigen-antibody complexes in hepatitis measured by complement fixation.

N. Raphael Shulman, +1 more
- 18 Jul 1969 - 
TL;DR: Complement fixation techniques are described for measuring a virus-like antigen associated with viral hepatitis, which was found in the blood of 98 percent of 130 patients, with the serum form of hepatitis, from whom multiple samples were obtained.
Journal ArticleDOI

Australia antigen as a hepatitis virus: Variation in host response

Baruch S. Blumberg, +2 more
- 01 Jan 1970 - 
TL;DR: The Australia antigen is a particle of about 200 A with the appearance of a virus and can be detected in the nuclei of liver cells of patients with hepatitis using fluorescent antibody technics.