Journal ArticleDOI
High-level exogenous glutamic acid-independent production of poly-(γ-glutamic acid) with organic acid addition in a new isolated Bacillus subtilis C10.
Huili Zhang,Jianzhong Zhu,Xiangcheng Zhu,Jin Cai,Anyi Zhang,Yizhi Hong,Jin Huang,Lei Huang,Zhinan Xu +8 more
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TLDR
The result indicated that the enhanced level of pyruvate dehydrogenase (PDH) activity caused by oxalic acid was important for glutamic acid synthesized de novo from glucose.About:
This article is published in Bioresource Technology.The article was published on 2012-07-01. It has received 59 citations till now. The article focuses on the topics: Glutamic acid & Pyruvate dehydrogenase complex.read more
Citations
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Poly-γ-glutamic acid: production, properties and applications.
TL;DR: Owing to its biodegradable, non-toxic and non-immunogenic properties, it has been used successfully in the food, medical and wastewater industries, and has the potential to be used for protein crystallization, as a soft tissue adhesive and a non-viral vector for safe gene delivery.
Journal ArticleDOI
Microbial synthesis of poly-γ-glutamic acid: current progress, challenges, and future perspectives.
TL;DR: A review of the properties, biosynthetic pathway, production strategies, and applications of poly-γ-glutamic acid (γ-PGA) is presented in this article.
Microbial synthesis of poly-γ-glutamic acid: current progress, challenges, and future
TL;DR: Genetic engineering and optimization of the growth medium, process control, and downstream processing have proved to be effective strategies for lowering the cost of production, as well as manipulating the molecular mass and conformational/enantiomeric properties that facilitate screening of competitive γ-PGA producers.
Journal ArticleDOI
Developing Bacillus spp. as a cell factory for production of microbial enzymes and industrially important biochemicals in the context of systems and synthetic biology
Long Liu,Yanfeng Liu,Hyun-Dong Shin,Rachel R. Chen,Nam Sun Wang,Jianghua Li,Guocheng Du,Jian Chen +7 more
TL;DR: The available genetic tools, engineering strategies, genome sequence, genome-scale structure models, proteome, and secretion pathways, and successful examples of enzymes and industrially important biochemicals produced by Bacillus spp.
Journal ArticleDOI
Microbial production of poly-γ-glutamic acid
Sarote Sirisansaneeyakul,Mingfeng Cao,Nuttawut Kongklom,Chaniga Chuensangjun,Zhongping Shi,Yusuf Chisti +5 more
TL;DR: This review is focused on nonrecombinant microbial production of γ-PGA via fermentation processes and the emphasis is on l-glutamic acid independent producers, but glutamic acid dependent production is discussed for comparison.
References
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Journal ArticleDOI
Colorimetric Method for Determination of Sugars and Related Substances
TL;DR: In this article, a method was developed to determine submicro amounts of sugars and related substances using a phenol-sulfuric acid reaction, which is useful for the determination of the composition of polysaccharides and their methyl derivatives.
Journal ArticleDOI
The production of poly-(γ-glutamic acid) from microorganisms and its various applications
Ing-Lung Shih,Yi-Tsong Van +1 more
TL;DR: In this article, the chemistry and biosynthesis of poly-(gamma-glutamic acid) (Gamma-PGA) produced by various strains of Bacillus are discussed.
Journal ArticleDOI
Production of a biopolymer flocculant from Bacillus licheniformis and its flocculation properties.
TL;DR: The comparison of the flocculating activity between the present biopolymers and a commercial lower molecular weight product showed that the biopolymer of the present study had much higher activity.
Journal ArticleDOI
Microbial Biosynthesis of Polyglutamic Acid Biopolymer and Applications in the Biopharmaceutical, Biomedical and Food Industries
TL;DR: An updated critical literature review on the production and applications of Polyglutamic Acid is provided, finding a great variety of applications for both isoforms of PGA.
Journal ArticleDOI
Natural and edible biopolymer poly‐γ‐glutamic acid: synthesis, production, and applications
TL;DR: In this paper, a review of the production of a strain of polyγ-glutamic acid and recent developments with respect to applications in terms of Ca absorption, moisturizing properties, γ-PGA conjugation, super absorbent polymer, and so on is presented.
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