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How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease
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The article was published on 2010-01-01 and is currently open access. It has received 1442 citations till now. The article focuses on the topics: Tobacco smoke.read more
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Measuring the effect of policy interventions at the population level: some methodological concerns
TL;DR: This work examines statewide admission rates for acute myocardial infarctions, strokes and lower limb fractures, and emergency room encounter rates for asthma exacerbations before and after the smoking ban in New Jersey.
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Towards the validation of a lung tumorigenesis model with mainstream cigarette smoke inhalation using the A/J mouse.
Walter Stinn,An Berges,Kris Meurrens,Ansgar Buettner,Stephan Gebel,Rosemarie B. Lichtner,Kris Janssens,Emilija Veljkovic,Yang Xiang,Ewald Roemer,Hans-Juergen Haussmann +10 more
TL;DR: The current data suggest that this model for MS inhalation-induced pulmonary tumorigenesis is reliable and relevant, two crucial requirements towards validation of such a model.
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Changes in levels of biomarkers of exposure observed in a controlled study of smokers switched from conventional to reduced toxicant prototype cigarettes
Christopher J. Shepperd,Alison Eldridge,Oscar M. Camacho,Kevin McAdam,Christopher Proctor,Ingo Meyer +5 more
TL;DR: Reductions in BoEs demonstrate that it is possible to produce prototype cigarettes that reduce exposure to toxicants in short-term use and to produce reduced toxicant prototype cigarettes with substantially reduced levels of tobacco smoke toxicants.
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Safety during breastfeeding: Drugs, foods, environmental chemicals, and maternal infections
TL;DR: Concern over any possible adverse event to the nursing infant should take into account the drug, its dose, the age of the infant, recognition of the interindividual variation in drug response and the role of pharmacogenetics.
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Assessment of the exposure to harmful and potentially harmful constituents in healthy Japanese smokers using a novel tobacco vapor product compared with conventional cigarettes and smoking abstinence.
TL;DR: The biomarkers of exposure (BoEs) were significantly reduced when switching to NTV, and the reductions in BoEs following switching to the NTV approached those following smoking abstinence.