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How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease
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The article was published on 2010-01-01 and is currently open access. It has received 1442 citations till now. The article focuses on the topics: Tobacco smoke.read more
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Journal ArticleDOI
Oxidative stress and skeletal muscle dysfunction are present in healthy smokers
Camila Danielle Cunha Neves,Ana Cristina R. Lacerda,Vanessa Kelly da Silva Lage,Liliana Pereira Lima,Rosalina Tossige-Gomes,Sueli Ferreira da Fonseca,Etel Rocha-Vieira,Mauro M. Teixeira,Vanessa Amaral Mendonça +8 more
TL;DR: Smokers presented increased oxidative stress and skeletal muscle dysfunction, demonstrating that the changes in molecular and muscular parameters occur simultaneously in healthy smokers.
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Highlights From a Workshop on Opportunities for Cancer Prevention During Preadolescence and Adolescence
TL;DR: A central theme of the workshop was that preadolescence and adolescence are times of unique susceptibility and vulnerability within the lifespan.
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Molecular changes in smoking-related lung cancer.
TL;DR: Accumulated evidence suggested that lung cancer in ever smokers and never smokers follow distinct molecular pathways and may therefore respond to distinct therapy.
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Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review.
TL;DR: It is concluded that the rating process presented is useful for selecting BOBEs suitable for risk evaluation of NTPs in clinical and other human studies.
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Differential DNA methylation in blood as a mediator of the association between cigarette smoking and bladder cancer risk among postmenopausal women
Kristina M. Jordahl,Kristina M. Jordahl,Amanda I. Phipps,Amanda I. Phipps,Timothy W. Randolph,Hilary A. Tindle,Simin Liu,Lesley F. Tinker,Karl T. Kelsey,Emily White,Emily White,Parveen Bhatti +11 more
TL;DR: This study investigates whether changes in DNA methylation, as measured in blood, mediate the impact of smoking on bladder cancer risk among postmenopausal women and suggests that differential methylation of cg05575921 and cg19859270 Mediate the effects ofsmoking on bladder cancers, potentially revealing downstream effects of smoking relevant for carcinogenesis.