Open Access
How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease
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The article was published on 2010-01-01 and is currently open access. It has received 1442 citations till now. The article focuses on the topics: Tobacco smoke.read more
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Journal ArticleDOI
Aerosol from Tobacco Heating System 2.2 has reduced impact on mouse heart gene expression compared with cigarette smoke.
Justyna Szostak,Stéphanie Boué,Marja Talikka,Emmanuel Guedj,Florian Martin,Blaine Phillips,Nikolai V. Ivanov,Manuel C. Peitsch,Julia Hoeng +8 more
TL;DR: Analysis of differentially expressed genes in the heart tissue indicated that 3R4F exposure induced the downregulation of genes involved in cytoskeleton organization and the contractile function of the heart, notably genes that encode beta actin, actinin alpha 4 (Actn4), and filamin C (Flnc).
Journal ArticleDOI
Short-Term Exposure to Waterpipe/Hookah Smoke Triggers a Hyperactive Platelet Activation State and Increases the Risk of Thrombogenesis
Ahmed B. Alarabi,Zubair A. Karim,Jean E. Montes Ramirez,Keziah R. Hernandez,Patricia A. Lozano,José O. Rivera,Fatima Z. Alshbool,Fadi T. Khasawneh +7 more
TL;DR: It is demonstrated that WPS exposure directly modulates hemostasis and increases the risk of thrombosis and that this is mediated, in part, via a state of platelet hyperactivity.
Journal ArticleDOI
Civil Society and Tobacco Control in Indonesia: The Last Resort
TL;DR: In this article, the authors discuss how mechanisms of civil society are a chance to at least improve the situa- tion and effectively combat a grave social problem, while smoking as an addic- tion seems to be declining in some countries, in others it is not.
Journal ArticleDOI
Cardiovascular Risk in Cancer Survivors.
TL;DR: The increased risk of CVD and CVD-related death in cancer survivors is likely to be multifactorial, involving cardiotoxic effects of cancer treatments as well as comorbidities and harmful lifestyle habits.
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Comparative and cumulative quantitative risk assessments on a novel heated tobacco product versus the 3R4F reference cigarette.
TL;DR: In this paper, the authors used a quantitative risk assessment approach to compare non-cancer and cancer risk estimates for emissions generated by an HTP with smoke from a reference cigarette (3R4F).